6n3s: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6n3s is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal structure of apo-cruzain==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6n3s]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N3S OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N3S FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Cruzipain Cruzipain], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.51 3.4.22.51] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n3s OCA], [http://pdbe.org/6n3s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n3s RCSB], [http://www.ebi.ac.uk/pdbsum/6n3s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n3s ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/CYSP_TRYCR CYSP_TRYCR]] Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group. The cysteine protease may play an important role in the development and differentiation of the parasites at several stages of their life cycle.

__TOC__

</StructureSection>

[[Category: Cruzipain]]

[[Category: Large Structures]]

[[Category: Brandstetter, H]]

[[Category: Dall, E]]

[[Category: Ferreira, R S]]

[[Category: Rodrigues, F T.G]]

[[Category: Silva, E B]]

[[Category: Apo cruzain]]

[[Category: Hydrolase]]

[[Category: Protease]]

[[Category: Thiol protease]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6n3s is ON HOLD  until Paper Publication
+==Crystal structure of apo-cruzain==
+<StructureSection load='6n3s' size='340' side='right'caption='[[6n3s]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6n3s]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N3S FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cruzipain Cruzipain], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.51 3.4.22.51] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n3s OCA], [http://pdbe.org/6n3s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n3s RCSB], [http://www.ebi.ac.uk/pdbsum/6n3s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n3s ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CYSP_TRYCR CYSP_TRYCR]] Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group.  The cysteine protease may play an important role in the development and differentiation of the parasites at several stages of their life cycle.
+__TOC__
+</StructureSection>
+[[Category: Cruzipain]]
+[[Category: Large Structures]]
+[[Category: Brandstetter, H]]
+[[Category: Dall, E]]
+[[Category: Ferreira, R S]]
+[[Category: Rodrigues, F T.G]]
+[[Category: Silva, E B]]
+[[Category: Apo cruzain]]
+[[Category: Hydrolase]]
+[[Category: Protease]]
+[[Category: Thiol protease]]