DAHP synthase: Difference between revisions

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The DAHPS active site is located in a channel at the C-terminal of the enzyme where the <scene name='70/708806/Cv/7'>substrate (PEP)</scene>, <scene name='70/708806/Cv/8'>inhibitor (phenylalanine)</scene> and <scene name='70/708806/Cv/9'>metal ion (Mn+2)</scene> are seen. The bivalent metal is bound to a Cys-X-X-His motif.<ref>PMID:12126632</ref>
The DAHPS active site is located in a channel at the C-terminal of the enzyme where the <scene name='70/708806/Cv/7'>substrate (PEP)</scene>, <scene name='70/708806/Cv/8'>inhibitor (phenylalanine)</scene> and <scene name='70/708806/Cv/9'>metal ion (Mn+2)</scene> are seen. The bivalent metal is bound to a Cys-X-X-His motif.<ref>PMID:12126632</ref>
== 3D Structures of DAHP synthase ==
[[DAHP synthase 3D structures]]


</StructureSection>
</StructureSection>
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**[[4ixx]] - NmDAHPS (mutant) + Mn <br />
**[[4ixx]] - NmDAHPS (mutant) + Mn <br />
**[[3tqk]] - DAHPS + Mn – ''Francisella tularensis''<br />
**[[3tqk]] - DAHPS + Mn – ''Francisella tularensis''<br />
**[[3nvt]] - LmDAHPS + Mn – ''Listeria monocytogenes''<br />


*DAHP synthase binary complex
*DAHP synthase binary complex
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**[[2w19]] - MtDAHPS + chorismate mutase <br />
**[[2w19]] - MtDAHPS + chorismate mutase <br />
**[[5huc]] - CgDAHPS + Mn + PEP – ''Corynebacterium glutamicum''<br />
**[[5huc]] - CgDAHPS + Mn + PEP – ''Corynebacterium glutamicum''<br />
**[[3tfc]] - LmDAHPS + Mn + PEP <br />


*DAHP synthase higher complex
*DAHP synthase higher complex

Revision as of 08:57, 3 June 2019

E. coli DAHP synthase complex with PEP, phenylalanine, sulfate and Mn+2 ion (PDB code 1kfl)

Drag the structure with the mouse to rotate

3D Structures of DAHP synthase

Updated on 03-June-2019

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman