4y30: Difference between revisions
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==Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and EPZ020411== | ==Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and EPZ020411== | ||
<StructureSection load='4y30' size='340' side='right' caption='[[4y30]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='4y30' size='340' side='right'caption='[[4y30]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4y30]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y30 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4y30]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y30 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=49L:N,N-DIMETHYL-N-({3-[4-({TRANS-3-[2-(TETRAHYDRO-2H-PYRAN-4-YL)ETHOXY]CYCLOBUTYL}OXY)PHENYL]-1H-PYRAZOL-4-YL}METHYL)ETHANE-1,2-DIAMINE'>49L</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=49L:N,N-DIMETHYL-N-({3-[4-({TRANS-3-[2-(TETRAHYDRO-2H-PYRAN-4-YL)ETHOXY]CYCLOBUTYL}OXY)PHENYL]-1H-PYRAZOL-4-YL}METHYL)ETHANE-1,2-DIAMINE'>49L</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y2h|4y2h]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y2h|4y2h]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRMT6, HRMT1L6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y30 OCA], [http://pdbe.org/4y30 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y30 RCSB], [http://www.ebi.ac.uk/pdbsum/4y30 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y30 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y30 OCA], [http://pdbe.org/4y30 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y30 RCSB], [http://www.ebi.ac.uk/pdbsum/4y30 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y30 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4y30" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4y30" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Histone methyltransferase|Histone methyltransferase]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Boriack-Sjodin, P A]] | [[Category: Boriack-Sjodin, P A]] | ||
[[Category: Swinger, K K]] | [[Category: Swinger, K K]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
