6o07: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Structure and mechanism of acetylation by the N-terminal dual enzyme NatA/Naa50 complex== | |||
<StructureSection load='6o07' size='340' side='right'caption='[[6o07]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6o07]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O07 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6O07 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-terminal_methionine_N(alpha)-acetyltransferase_NatE N-terminal methionine N(alpha)-acetyltransferase NatE], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.258 2.3.1.258] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6o07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o07 OCA], [http://pdbe.org/6o07 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6o07 RCSB], [http://www.ebi.ac.uk/pdbsum/6o07 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6o07 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/NAT5_YEAST NAT5_YEAST]] Non-essential component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover. [[http://www.uniprot.org/uniprot/ARD1_YEAST ARD1_YEAST]] Catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover.<ref>PMID:1600941</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Deng, S]] | |||
[[Category: Marmorstein, R]] | |||
[[Category: N-terminal acetylation]] | |||
[[Category: Naa50]] | |||
[[Category: Nata]] | |||
[[Category: Nate]] | |||
[[Category: Protein complex]] | |||
[[Category: Transferase]] | |||
Revision as of 05:42, 12 June 2019
Structure and mechanism of acetylation by the N-terminal dual enzyme NatA/Naa50 complex
| ||||||||||||
