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==Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 3b==
==Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 3b==
<StructureSection load='5nkf' size='340' side='right' caption='[[5nkf]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
<StructureSection load='5nkf' size='340' side='right'caption='[[5nkf]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5nkf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NKF FirstGlance]. <br>
<table><tr><td colspan='2'>[[5nkf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NKF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8ZN:~{N}-(2-chloranyl-6-methyl-phenyl)-2-[[3-(piperidin-4-ylcarbamoyl)-5-(trifluoromethyl)phenyl]amino]-1,3-thiazole-5-carboxamide'>8ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8ZN:~{N}-(2-chloranyl-6-methyl-phenyl)-2-[[3-(piperidin-4-ylcarbamoyl)-5-(trifluoromethyl)phenyl]amino]-1,3-thiazole-5-carboxamide'>8ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EPHA2, ECK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nkf OCA], [http://pdbe.org/5nkf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nkf RCSB], [http://www.ebi.ac.uk/pdbsum/5nkf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nkf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nkf OCA], [http://pdbe.org/5nkf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nkf RCSB], [http://www.ebi.ac.uk/pdbsum/5nkf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nkf ProSAT]</span></td></tr>
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</div>
</div>
<div class="pdbe-citations 5nkf" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5nkf" style="background-color:#fffaf0;"></div>
==See Also==
*[[Ephrin receptor|Ephrin receptor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: GANDE, S L]]
[[Category: Gande, S L]]
[[Category: HEINZLMEIR, S]]
[[Category: Heinzlmeir, S]]
[[Category: KUDLINZKI, D]]
[[Category: Kudlinzki, D]]
[[Category: KUESTER, B]]
[[Category: Kuester, B]]
[[Category: LINHARD, V L]]
[[Category: Linhard, V L]]
[[Category: MEDARD, G]]
[[Category: Medard, G]]
[[Category: SAXENA, K]]
[[Category: Saxena, K]]
[[Category: SCHWALBE, H]]
[[Category: Schwalbe, H]]
[[Category: WITT, K]]
[[Category: Witt, K]]
[[Category: Complex]]
[[Category: Complex]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]
[[Category: Protein tyrosine kinase]]
[[Category: Protein tyrosine kinase]]
[[Category: Transferase]]
[[Category: Transferase]]