Nanog: Difference between revisions

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== Function ==

The expression of Nanog is detectable at embryonic day 6. It is expressed in the proximal epiblast in a region presumed to be the primitive streak, its expression extends distally as the streak elongates during gastrulation and remains restricted to epiblast. Nanog is vital to maintain pluripotency, it is very much needed, since nanog-deficient inner cell mass from the blastocyst could not generate epiblast and only produce parietal endoderm-like cells. Meanwhile, Nanog-deficient embryonic stem cells lost pluripotency and differentiated into extraembryonic endoderm lineage. [5]

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Revision as of 20:04, 12 June 2019 view source Thiago Giove Mitsugi (talk \| contribs) 9 edits New page: ==Nanog (Human homeobox protein)== <StructureSection load='4rbo' size='340' side='right' caption='Caption for this structure' scene=''> NANOG is a transcription factor, an upstream regulat...		Revision as of 20:07, 12 June 2019 view source Thiago Giove Mitsugi (talk \| contribs) 9 edits No edit summary Newer edit →
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	== Function ==		== Function ==
	The expression of Nanog is detectable at embryonic day 6. It is expressed in the proximal epiblast in a region presumed to be the primitive streak, its expression extends distally as the streak elongates during gastrulation and remains restricted to epiblast. Nanog is vital to maintain pluripotency, it is very much needed, since nanog-deficient inner cell mass from the blastocyst could not generate epiblast and only produce parietal endoderm-like cells. Meanwhile, Nanog-deficient embryonic stem cells lost pluripotency and differentiated into extraembryonic endoderm lineage. [5]		The expression of Nanog is detectable at embryonic day 6. It is expressed in the proximal epiblast in a region presumed to be the primitive streak, its expression extends distally as the streak elongates during gastrulation and remains restricted to epiblast. Nanog is vital to maintain pluripotency, it is very much needed, since nanog-deficient inner cell mass from the blastocyst could not generate epiblast and only produce parietal endoderm-like cells. Meanwhile, Nanog-deficient embryonic stem cells lost pluripotency and differentiated into extraembryonic endoderm lineage. [5]