6jy5: Difference between revisions
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==Structure of CsoS4B from Halothiobacillus neapolitanus== | |||
<StructureSection load='6jy5' size='340' side='right'caption='[[6jy5]], [[Resolution|resolution]] 2.15Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6jy5]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JY5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JY5 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jy5 OCA], [http://pdbe.org/6jy5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jy5 RCSB], [http://www.ebi.ac.uk/pdbsum/6jy5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jy5 ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Carboxysome, encapsulating an enzymatic core within an icosahedral-shaped semipermeable protein shell, could enhance CO2 fixation under low CO2 conditions in the environment. The shell of Halothiobacillus neapolitanus alpha-carboxysome possesses two 38% sequence-identical pentameric proteins, namely CsoS4A and CsoS4B. However, the functions of two paralogous pentameric proteins in alpha-carboxysome assembly remain unknown. Here we report the crystal structure of CsoS4B at 2.15A resolution. It displays as a stable pentamer, each subunit of which consists of a beta-barrel core domain, in addition to an insertion of helix alpha1 that forms the central pore. Structural comparisons and multiple-sequence alignment strongly indicate that CsoS4A and CsoS4B differ from each other in interacting with various components of alpha-carboxysome, despite they share a similar overall structure. These findings provide the structural basis for further investigations on the self-assembly process of carboxysome. | |||
Crystal structure of pentameric shell protein CsoS4B of Halothiobacillus neapolitanus alpha-carboxysome.,Zhao YY, Jiang YL, Chen Y, Zhou CZ, Li Q Biochem Biophys Res Commun. 2019 Jul 30;515(3):510-515. doi:, 10.1016/j.bbrc.2019.05.047. Epub 2019 Jun 3. PMID:31171360<ref>PMID:31171360</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
[[Category: | <div class="pdbe-citations 6jy5" style="background-color:#fffaf0;"></div> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Chen, Y]] | [[Category: Chen, Y]] | ||
[[Category: Jiang, Y | [[Category: Jiang, Y L]] | ||
[[Category: Li, Q]] | [[Category: Li, Q]] | ||
[[Category: Zhou, C | [[Category: Zhao, Y Y]] | ||
[[Category: Zhou, C Z]] | |||
[[Category: Carboxysome shell protein]] | |||
[[Category: Pentameric protein]] | |||
[[Category: Structural protein]] | |||
Revision as of 06:54, 26 June 2019
Structure of CsoS4B from Halothiobacillus neapolitanus
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