6p9e: Difference between revisions

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'''Unreleased structure'''


The entry 6p9e is ON HOLD
==Crystal structure of IL-36gamma complexed to A-552==
 
<StructureSection load='6p9e' size='340' side='right'caption='[[6p9e]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
Authors: Argiriadi, M.A., Todorovic, T., Su, Z., Putman, B., Kakavas, S.J., Salte, K.M., McDonald, H.A., Wetter, J.B., Paulsboe, S.E., Sun, Q., Gerstein, C.E., Medina, L., Sielaff, B., Sadhukhan, R., Stockmann, H., Richardson, P.L., Qiu, W., Henry, R.F., Herold, J.M., Shotwell, J.B., McGaraughty, S.P., Honore, P., Gopalakrishnan, S.M., Sun, C.C., Scott, V.E.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6p9e]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P9E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6P9E FirstGlance]. <br>
Description: Crystal structure of IL-36gamma complexed to A-552
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=O6D:(2S)-2-{[4-(3-amino-4-methylphenyl)-6-methylpyrimidin-2-yl]oxy}-3-methoxy-3,3-diphenylpropanoic+acid'>O6D</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6p9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p9e OCA], [http://pdbe.org/6p9e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p9e RCSB], [http://www.ebi.ac.uk/pdbsum/6p9e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p9e ProSAT]</span></td></tr>
[[Category: Herold, J.M]]
</table>
[[Category: Wetter, J.B]]
== Function ==
[[http://www.uniprot.org/uniprot/IL36G_HUMAN IL36G_HUMAN]] Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2/IL1RL2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.  
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Argiriadi, M A]]
[[Category: Gerstein, C E]]
[[Category: Gopalakrishnan, S M]]
[[Category: Henry, R F]]
[[Category: Herold, J M]]
[[Category: Honore, P]]
[[Category: Kakavas, S J]]
[[Category: McDonald, H A]]
[[Category: McGaraughty, S P]]
[[Category: Medina, L]]
[[Category: Medina, L]]
[[Category: Paulsboe, S E]]
[[Category: Putman, B]]
[[Category: Qiu, W]]
[[Category: Richardson, P L]]
[[Category: Sadhukhan, R]]
[[Category: Salte, K M]]
[[Category: Scott, V E]]
[[Category: Shotwell, J B]]
[[Category: Sielaff, B]]
[[Category: Stockmann, H]]
[[Category: Su, Z]]
[[Category: Su, Z]]
[[Category: Honore, P]]
[[Category: Sun, C C]]
[[Category: Mcgaraughty, S.P]]
[[Category: Sielaff, B]]
[[Category: Scott, V.E]]
[[Category: Gopalakrishnan, S.M]]
[[Category: Sadhukhan, R]]
[[Category: Gerstein, C.E]]
[[Category: Putman, B]]
[[Category: Shotwell, J.B]]
[[Category: Paulsboe, S.E]]
[[Category: Sun, Q]]
[[Category: Sun, Q]]
[[Category: Sun, C.C]]
[[Category: Todorovic, T]]
[[Category: Todorovic, T]]
[[Category: Kakavas, S.J]]
[[Category: Wetter, J B]]
[[Category: Qiu, W]]
[[Category: Cytokine]]
[[Category: Argiriadi, M.A]]
[[Category: Il-36]]
[[Category: Stockmann, H]]
[[Category: Small molecule antagonist]]
[[Category: Salte, K.M]]
[[Category: Richardson, P.L]]
[[Category: Henry, R.F]]
[[Category: Mcdonald, H.A]]
Retrieved from "https://proteopedia.org/6p9e"