4zvv: Difference between revisions
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==Lactate dehydrogenase A in complex with a trisubstituted piperidine-2,4-dione inhibitor GNE-140== | ==Lactate dehydrogenase A in complex with a trisubstituted piperidine-2,4-dione inhibitor GNE-140== | ||
<StructureSection load='4zvv' size='340' side='right' caption='[[4zvv]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='4zvv' size='340' side='right'caption='[[4zvv]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4zvv]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZVV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZVV FirstGlance]. <br> | <table><tr><td colspan='2'>[[4zvv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZVV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZVV FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GN0:(2~{R})-5-(2-CHLOROPHENYL)SULFANYL-2-(4-MORPHOLIN-4-YLPHENYL)-4-OXIDANYL-2-THIOPHEN-3-YL-1,3-DIHYDROPYRIDIN-6-ONE'>GN0</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GN0:(2~{R})-5-(2-CHLOROPHENYL)SULFANYL-2-(4-MORPHOLIN-4-YLPHENYL)-4-OXIDANYL-2-THIOPHEN-3-YL-1,3-DIHYDROPYRIDIN-6-ONE'>GN0</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LDHA, PIG19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zvv OCA], [http://pdbe.org/4zvv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zvv RCSB], [http://www.ebi.ac.uk/pdbsum/4zvv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zvv ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zvv OCA], [http://pdbe.org/4zvv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zvv RCSB], [http://www.ebi.ac.uk/pdbsum/4zvv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zvv ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4zvv" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4zvv" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Lactate Dehydrogenase|Lactate Dehydrogenase]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: L-lactate dehydrogenase]] | [[Category: L-lactate dehydrogenase]] | ||
[[Category: Large Structures]] | |||
[[Category: Chen, Z]] | [[Category: Chen, Z]] | ||
[[Category: Eigenbrot, C]] | [[Category: Eigenbrot, C]] | ||
