4zsr: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==BACE crystal structure with tricyclic aminothiazine inhibitor== | ==BACE crystal structure with tricyclic aminothiazine inhibitor== | ||
<StructureSection load='4zsr' size='340' side='right' caption='[[4zsr]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='4zsr' size='340' side='right'caption='[[4zsr]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4zsr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZSR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZSR FirstGlance]. <br> | <table><tr><td colspan='2'>[[4zsr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZSR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZSR FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4RY:N-[(4AS,6S,8AR)-2-AMINO-5,6,7,8-TETRAHYDRO-4A,8A-(METHANOOXYMETHANO)-3,1-BENZOTHIAZIN-6(4H)-YL]-3-CHLOROBENZAMIDE'>4RY</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4RY:N-[(4AS,6S,8AR)-2-AMINO-5,6,7,8-TETRAHYDRO-4A,8A-(METHANOOXYMETHANO)-3,1-BENZOTHIAZIN-6(4H)-YL]-3-CHLOROBENZAMIDE'>4RY</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zsm|4zsm]], [[4zsp|4zsp]], [[4zsq|4zsq]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zsm|4zsm]], [[4zsp|4zsp]], [[4zsq|4zsq]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACE1, BACE, KIAA1149 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zsr OCA], [http://pdbe.org/4zsr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zsr RCSB], [http://www.ebi.ac.uk/pdbsum/4zsr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zsr ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zsr OCA], [http://pdbe.org/4zsr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zsr RCSB], [http://www.ebi.ac.uk/pdbsum/4zsr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zsr ProSAT]</span></td></tr> | ||
| Line 20: | Line 21: | ||
</div> | </div> | ||
<div class="pdbe-citations 4zsr" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4zsr" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Beta secretase 3D structures|Beta secretase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Timm, D E]] | [[Category: Timm, D E]] | ||
