Farnesyltransferase: Difference between revisions

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</StructureSection>
</StructureSection>
==3D structures of farnesyltransferase==


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*FTase
**[[1ft1]] – rFTase – rat<br />
**[[3q73]] – CnFTase – ''Cryptococcus neoformans''
*FTase binary complex with FPP
**[[1ft2]], [[1fpp]] – rFTase + FPP<BR />
**[[1o1r]], [[1o1s]], [[3ksl]], [[3ksq]] - rFTase + FPP-analog<br />
*FTase binary complex with peptide
**[[1kzp]], [[1o1t]] - rFTase + farnesylated peptide<br />
**[[2h6f]] - hFTase + farnesylated peptide<br />
**[[2h6g]], [[2h6h]], [[2h6i]] - hFTase α subunit + β subunit (mutant) + farnesylated peptide<br />
**[[3q79]] - CnFTase + farnesylated peptide
*FTase binary complex with inhibitor
**[[3eu5]] – rFTase + biotin-GPP<br />
**[[3euv]] - rFTase α subunit + β subunit (mutant)+ biotin-GPP<br />
**[[1n94]], [[1n95]], [[1n9a]], [[1o5m]], [[1ni1]], [[1x81]], [[2bed]], [[2r2l]] - rFTase + inhibitor<br />
**[[1nl4]] - rFTase α subunit (mutant) + β subunit + inhibitor
*FTase ternary complex with FPP and peptide
**[[1d8d]], [[1tn8]] - rFTase + Ras peptide + FPP-analog<br />
**[[1kzo]] - rFTase + farnesylated Ras peptide + FPP<BR />
**[[1tn7]], [[3dpy]] - rFTase + peptide + FPP-analog<BR />
**[[1jcr]], [[1jcs]] - rFTase + tetrapeptide inhibitor + FPP<BR />
**[[1d8e]] - rFTase no Zn + Ras peptide + FPP-analog<br />
**[[1tn6]] - hFTase + Rap2a peptide + FPP-analog<br />
**[[3q75]], [[3q78]] - CnFTase + peptide + FPP-analog<br />
**[[4l9p]] - AfFTase + peptide + FPP-analog – ''Apergillus fumigatus''<br />
*FTase ternary complex with FPP and inhibitor
**[[1sa5]], [[3e30]], [[3e32]], [[3e33]], [[3e34]], [[3e37]] - rFTase + inhibitor + FPP<BR />
**[[4gtm]], [[4gto]], [[4gtp]], [[4gtq]], [[4gtr]] - rFTase α subunit + β subunit + inhibitor + FPP<br />
**[[2zir]], [[2zis]] - rFTase α subunit (mutant) + β subunit + inhibitor + FPP<BR />
**[[1jcq]] – hFTase α subunit (mutant) + β subunit + inhibitor + FPP– human<br />
**[[1ld7]], [[1ld8]], [[1mzc]], [[1sa4]], [[1s63]], [[2f0y]] - hFTase + inhibitor + FPP<BR />
**[[2iej]] - hFTase + inhibitor + FPP-analog<br />
**[[3pz4]] - FTase + inhibitor + FPP – mouse<br />
**[[3q7a]], [[3q7f]] - CnFTase + inhibitor + FPP<BR />
**[[3fsx]], [[3sfy]] - CnFTase + inhibitor + FPP-analog<br />
**[[3sfx]] - CnFTase α subunit + β subunit + inhibitor + FPP<br />
**[[4lnb]], [[4lng]], [[4mbg]] - AfFTase (mutant) + inhibitor + FPP<br />
*FTase ternary complex with GPP and protein
**[[1n4p]], [[1n4r]], [[1n4s]] - rFTase α subunit + GTase β subunit + transforming protein + GPP<br />
}}
== References ==
== References ==
<references/>
<references/>


[[Category:Topic Page]]
[[Category:Topic Page]]

Latest revision as of 08:47, 26 June 2019

Farnesyltransferaseα subunit (cyan) and β subunit (green) complex with farnesyl diphosphate (FPP) analog, Zn+2 ion (grey), sulfonic acid derivative and CAAX peptide (PDB code 3q75)

Drag the structure with the mouse to rotate

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman