5ans: Difference between revisions
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==Potent and selective inhibitors of MTH1 probe its role in cancer cell survival== | ==Potent and selective inhibitors of MTH1 probe its role in cancer cell survival== | ||
<StructureSection load='5ans' size='340' side='right' caption='[[5ans]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='5ans' size='340' side='right'caption='[[5ans]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5ans]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ANS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ANS FirstGlance]. <br> | <table><tr><td colspan='2'>[[5ans]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ANS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ANS FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RX8:1-[4-AMINO-2-(ETHOXYMETHYL)-1H-IMIDAZO[4,5-C]QUINOLIN-1-YL]-2-METHYLPROPAN-2-OL'>RX8</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RX8:1-[4-AMINO-2-(ETHOXYMETHYL)-1H-IMIDAZO[4,5-C]QUINOLIN-1-YL]-2-METHYLPROPAN-2-OL'>RX8</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5anm|5anm]], [[5ant|5ant]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5anm|5anm]], [[5ant|5ant]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/8-oxo-dGTP_diphosphatase 8-oxo-dGTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.55 3.6.1.55] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/8-oxo-dGTP_diphosphatase 8-oxo-dGTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.55 3.6.1.55] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ans FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ans OCA], [http://pdbe.org/5ans PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ans RCSB], [http://www.ebi.ac.uk/pdbsum/5ans PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ans FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ans OCA], [http://pdbe.org/5ans PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ans RCSB], [http://www.ebi.ac.uk/pdbsum/5ans PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ans ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5ans" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5ans" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[7%2C8-dihydro-8-oxoguanine triphosphatase 3D structures|7%2C8-dihydro-8-oxoguanine triphosphatase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: 8-oxo-dGTP diphosphatase]] | [[Category: 8-oxo-dGTP diphosphatase]] | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Alwan, H]] | [[Category: Alwan, H]] | ||
[[Category: Bista, M]] | [[Category: Bista, M]] | ||
