6qf4: Difference between revisions

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'''Unreleased structure'''


The entry 6qf4 is ON HOLD  until Paper Publication
==X-Ray structure of human Serine/Threonine Kinase 17B (STK17B) aka DRAK2 in complex with ADP obtained by on-chip soaking==
 
<StructureSection load='6qf4' size='340' side='right'caption='[[6qf4]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
Authors: Lieske, J., Cerv, M., Kreida, S., Barthelmess, M., Fischer, P., Pakendorf, T., Yefanov, O., Mariani, V., Seine, T., Ross, B.H., Crosas, E., Lorbeer, O., Burkhardt, A., Lane, T.J., Guenther, S., Bergtholdt, J., Schoen, S., Tornroth-Horsefield, S., Chapman, H.N., Meents, A.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6qf4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QF4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QF4 FirstGlance]. <br>
Description: X-Ray structure of human Serine/Threonine Kinase 17B (STK17B) aka DRAK2 in complex with ADP obtained by on-chip soaking
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qf1|6qf1]], [[6qf2|6qf2]], [[6qf3|6qf3]]</td></tr>
[[Category: Schoen, S]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qf4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qf4 OCA], [http://pdbe.org/6qf4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qf4 RCSB], [http://www.ebi.ac.uk/pdbsum/6qf4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qf4 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/ST17B_HUMAN ST17B_HUMAN]] Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.<ref>PMID:9786912</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Barthelmess, M]]
[[Category: Bergtholdt, J]]
[[Category: Burkhardt, A]]
[[Category: Cerv, M]]
[[Category: Chapman, H N]]
[[Category: Crosas, E]]
[[Category: Crosas, E]]
[[Category: Fischer, P]]
[[Category: Guenther, S]]
[[Category: Kreida, S]]
[[Category: Lane, T J]]
[[Category: Lieske, J]]
[[Category: Lorbeer, O]]
[[Category: Lorbeer, O]]
[[Category: Kreida, S]]
[[Category: Mariani, V]]
[[Category: Meents, A]]
[[Category: Pakendorf, T]]
[[Category: Ross, B H]]
[[Category: Schoen, S]]
[[Category: Seine, T]]
[[Category: Seine, T]]
[[Category: Chapman, H.N]]
[[Category: Burkhardt, A]]
[[Category: Cerv, M]]
[[Category: Tornroth-Horsefield, S]]
[[Category: Tornroth-Horsefield, S]]
[[Category: Pakendorf, T]]
[[Category: Ross, B.H]]
[[Category: Yefanov, O]]
[[Category: Yefanov, O]]
[[Category: Bergtholdt, J]]
[[Category: Adp]]
[[Category: Lieske, J]]
[[Category: Drak2]]
[[Category: Lane, T.J]]
[[Category: On-chip ligand soaking]]
[[Category: Fischer, P]]
[[Category: Stk17b]]
[[Category: Meents, A]]
[[Category: Transferase]]
[[Category: Mariani, V]]
[[Category: Barthelmess, M]]
[[Category: Guenther, S]]

Revision as of 05:54, 10 July 2019

X-Ray structure of human Serine/Threonine Kinase 17B (STK17B) aka DRAK2 in complex with ADP obtained by on-chip soaking

6qf4, resolution 2.50Å

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