Glycated hemoglobin: Difference between revisions
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New page: '''Glycated Hemoglobin''' is a form of hemoglobin with sugars attached to certain amino acid side chains. When blood sugar levels in an individual are high for long periods of time (hy... |
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==Structure== | ==Structure== | ||
<StructureSection load='5HY8' size='340' side='right' caption='Glycated hemoglobin (PDB ID 5hy8)' scene=''> | <StructureSection load='5HY8' size='340' side='right' caption='Glycated hemoglobin (PDB ID 5hy8)' scene=''> | ||
Hemoglobin is the protein that transports oxygen in our blood. In the <scene name='82/821067/Overall/1'>structure shown here</scene>, all four heme groups bind to oxygen. There amino acid side chains are covalently bound to a sugar molecule (they are glycated), indicating that this protein experienced high sugar levels for a long time. The sugars are glucose and fructose, and they are bound via a glycosidic bond to the sidechains of tyrosine and threonine. | |||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
