Gp41

spinqualitylabelsall models Core structure of acetylated gp41 from the HIV envelope glycoprotein, 1aik. Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Gp41 is a subunit of the envelope protein of retrovirus. Gp41 is a transmembrane protein and contains several sites which are involved in the infection of the host cells. Gp160 is the cleavable precursor of Gp41 and Gp120. For more details see Hiv env proteins. Relevance Fusion inhibitory drugs which bind to Gp41 prevent the attachment of the HIV-1 virus to the cell. 3D Structures of Gp41 Gp41 3D Structures

3D Structures of Gp41

Updated on 17-July-2019

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• Gp41 from HIV-1; Domains – core 509-661; N-peptide 541-590; transmembrane 670-709; tail 750-854
  • Hiv env proteins, Gp41 3D Structures – Gp41 N-terminal residues 1-49
    
  • 3k9a – Gp41 residues 1-108 (mutant)
    
  • 1aik, 1df4, 1df5, 1qr8, 1qr9, 1dlb, 1jpx, 1szt, 3vu5, 3vu6 - Gp41 N-peptide domain
    
  • 1env, 3cp1, 3cyo, 1f23, 1k33, 1k34, 1i5x, 1i5y, 2ot5, 5ka6, 5ka5, 4i2l – Gp41 N-peptide domain (mutant)
    
  • 2z2t, 2zzo, 3aha, 3vie, 2r3c, 2r5b, 2r5d, 3l36, 3l37, 3vgy, 3vh7, 3vtp, 5h0n, 5zpw – Gp41 N-peptide domain + fusion inhibitor peptide
    
  • 6b3u, 6dln – Gp41 transmembrane domain - NMR
    
  • 5vwl – Gp41 tail domain - NMR
    
  • 5v8l, 5v8m, 5uty, 5utf, 5um8, 5jsa, 5js9, 5i8h, 5d9q, 5cjx, 5c7k, 6ck9, 6chb, 6ch9, 6ch8, 6ch7, 5w6d, 4nrx, 5fyk, 5fyj, 4nco, 6mdt, 6mco – Gp41 core + Gp120 + antibody
    
  • 6nnj, 6nnf, 6nm6 – Gp41 core (mutant) + Gp120 + antibody
    
  • 6cdi, 6orn, 6oo, 6orp, 6orq, 6okp, 6nqd, 6mn7, 6cuf, 6cue – Gp41 core + Gp120 + antibody – Cryo EM
    
  • 6nc3, 6nc2 – Gp41 core (mutant) + Gp120 + antibody – Cryo EM
    
  • 5u1f, 5thr – Gp41 core + Gp120 + antibody + CD4
    
  • 5hm1 – Gp41 core + llama antibody
    
  • 3o3x – arGp41 - artificial
    
  • 4dzu – arGp41 + 3-α
    
  • 4dzv – arGp41 + 4-α/β
    
• Gp41 from Simian Immunodeficiency Virus
  • 2siv – Gp41 core
    
  • 2ezo, 2ezp, 2ezq, 2ezr, 2ezs, 1qce – Gp41 core - NMR
    
  • 1qbz, 1jq0 – Gp41 core (mutant)
    

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