6d68: Difference between revisions
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==Ube2G1 in complex with ubiquitin variant Ubv.G1.1== | |||
<StructureSection load='6d68' size='340' side='right'caption='[[6d68]], [[Resolution|resolution]] 2.36Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6d68]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D68 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D68 FirstGlance]. <br> | |||
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/E2_ubiquitin-conjugating_enzyme E2 ubiquitin-conjugating enzyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.23 2.3.2.23] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d68 OCA], [http://pdbe.org/6d68 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d68 RCSB], [http://www.ebi.ac.uk/pdbsum/6d68 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d68 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/UB2G1_HUMAN UB2G1_HUMAN]] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4.<ref>PMID:19103148</ref> <ref>PMID:20061386</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: E2 ubiquitin-conjugating enzyme]] | |||
[[Category: Large Structures]] | |||
[[Category: Ceccarelli, D F]] | |||
[[Category: Garg, P]] | |||
[[Category: Sicheri, F]] | [[Category: Sicheri, F]] | ||
[[Category: Sidhu, S]] | [[Category: Sidhu, S]] | ||
[[Category: | [[Category: Transferase]] | ||
[[Category: | [[Category: Ube2g1]] | ||
[[Category: Ubiquitin]] | |||
[[Category: Ubiquitin conjugating enzyme]] | |||
[[Category: Ubiquitin variant]] | |||
Revision as of 10:36, 17 July 2019
Ube2G1 in complex with ubiquitin variant Ubv.G1.1
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