Helicase: Difference between revisions

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*DNA helicase II or UvrD
*DNA helicase II or UvrD


**[[1q2z]], [[1rw2]] – hHel II KU86 C terminal – human - NMR<BR />
**[[5y58]] – yHel II + DNA – yeast<br />
**[[5y59]] – yHel II subunit 2 + Sir4P peptide<br />
**[[3lfu]] – EcHel II <BR />
**[[3lfu]] – EcHel II <BR />
**[[2is1]], [[2is2]] - EcHel II (mutant) + DNA<BR />
**[[2is1]], [[2is2]] - EcHel II (mutant) + DNA<BR />
**[[2is4]], [[2is6]] - EcHel II (mutant) + ADP + DNA<BR />
**[[2is4]], [[2is6]] - EcHel II (mutant) + ADP + DNA<BR />
**[[4c2t]], [[4c2u]], [[4c30]] – DrHel II + DNA - ''Deinococcus radiodurans''<br />
**[[4c2t]], [[4c2u]], [[4c30]] – DrHel II + DNA - ''Deinococcus radiodurans''<br />
**[[1q2z]], [[1rw2]] – hHel II KU86 C terminal – NMR<BR />
**[[5y58]] – yHel II + DNA – yeast<br />
**[[5y59]] – yHel II subunit 2 + Sir4P peptide<br />


*ATP-dependent helicase ATRX
*ATP-dependent helicase ATRX
Line 137: Line 137:
*ATP-dependent helicase CHD
*ATP-dependent helicase CHD


**[[2h1e]], [[2xb0]], [[3mwy]] – yCHD1 chromodomain<BR />
**[[2dy7]] - yCHD1 chromodomain 1 – NMR<BR />
**[[2dy8]] - yCHD1 chromodomain 2 – NMR<BR />
**[[3ted]] - yCHD1 chromodomain 1 + DNA<br />
**[[2b2y]] – hCHD1 <br />
**[[2b2y]] – hCHD1 <br />
**[[4b4c]] – hCHD1 DNA-binding domain<br />
**[[4b4c]] – hCHD1 DNA-binding domain<br />
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**[[2dl6]] – hCHD8 BRK domain - NMR <br />
**[[2dl6]] – hCHD8 BRK domain - NMR <br />
**[[2cka]] – hCHD8 <br />
**[[2cka]] – hCHD8 <br />
**[[2h1e]], [[2xb0]], [[3mwy]] – yCHD1 chromodomain<BR />
**[[2dy7]] - yCHD1 chromodomain 1 – NMR<BR />
**[[2dy8]] - yCHD1 chromodomain 2 – NMR<BR />
**[[3ted]] - yCHD1 chromodomain 1 + DNA<br />


*ATP-dependent DNA helicase PIF1
*ATP-dependent DNA helicase PIF1
Line 169: Line 169:
*Dead box ATP-dependent RNA helicase
*Dead box ATP-dependent RNA helicase


**[[3fho]] – DBP5 – fission yeast<BR />
**[[2kbe]] – yDBP5 N terminal – NMR<BR />
**[[2kbf]] - yDBP5 C terminal – NMR<BR />
**[[3gfp]] - yDBP5 C-terminal<BR />
**[[4xw3]] – hDDX1 SPRY domain<br />
**[[4xw3]] – hDDX1 SPRY domain<br />
**[[2i4i]] – hDDX3X residues 167-581<BR />
**[[2i4i]] – hDDX3X residues 167-581<BR />
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**[[2e29]], [[2m3d]] - hDDX50 GUCT domain - NMR<BR />
**[[2e29]], [[2m3d]] - hDDX50 GUCT domain - NMR<BR />
**[[1vec]] – hP54 N terminal<BR />
**[[1vec]] – hP54 N terminal<BR />
**[[3fho]] – DBP5 – fission yeast<BR />
**[[2kbe]] – yDBP5 N terminal – NMR<BR />
**[[2kbf]] - yDBP5 C terminal – NMR<BR />
**[[3gfp]] - yDBP5 C-terminal<BR />
**[[2hjv]] – BsDBPA domain 2 – ''Bacillus subtilis''<BR />
**[[2hjv]] – BsDBPA domain 2 – ''Bacillus subtilis''<BR />
**[[2g0c]] - BsDBPA RNA-binding domain<br />
**[[2g0c]] - BsDBPA RNA-binding domain<br />
Line 197: Line 197:
*''Dead box ATP-dependent RNA helicase complexes''
*''Dead box ATP-dependent RNA helicase complexes''


**[[3fmo]], [[3fhc]] – hDBP5 + Nup214<BR />
**[[3fht]] – hDBP5 + AMPPNP + RNA<BR />
**[[3fmp]] – hDDX19B + Nup214<br />
**[[3g0h]] – hDDX19B residues 54-275 + ATP analog + RNA<BR />
**[[3ews]] - hDDX19B residues 54-275 + ADP<BR />
**[[5e7m]], [[5e7j]] – hDDX3X catalytic domain + nucleotide<br />
**[[3dkp]] – hDDX52 domain I + ADP<BR />
**[[2wax]], [[2way]] – hDDX6 C terminal + EDC3-FDF peptide<BR />
**[[2j0s]], [[2j0q]], [[2hyi]] – hDDX48 + protein mago nashi homolog + RNA-binding protein 8A + protein CASC3 + RNA<BR />
**[[2j0u]] - hDDX48 + protein CASC3<BR />
**[[2db3]] – DmVASA residues 200-623 + RNA – ''Drosophila melanogaster''<br />
**[[5nt7]] – DmVASA RecA-like domain + maternal effect protein<br />
**[[3rrm]] – yDBP5 residues 91-482 (mutant) + GLE1 + NUP159 + ADP + IP6<BR />
**[[3rrm]] – yDBP5 residues 91-482 (mutant) + GLE1 + NUP159 + ADP + IP6<BR />
**[[3rrn]] - yDBP5 residues 91-482 (mutant) + GLE1 + IP6<BR />
**[[3rrn]] - yDBP5 residues 91-482 (mutant) + GLE1 + IP6<BR />
Line 212: Line 224:
**[[5lta]] - CtPrp43 + ADP + RNA<br />
**[[5lta]] - CtPrp43 + ADP + RNA<br />
**[[3jrv]] – DDX3X + protein K7 – Vaccinia virus<BR />
**[[3jrv]] – DDX3X + protein K7 – Vaccinia virus<BR />
**[[3fmo]], [[3fhc]] – hDBP5 + Nup214<BR />
**[[3fht]] – hDBP5 + AMPPNP + RNA<BR />
**[[3fmp]] – hDDX19B + Nup214<br />
**[[3g0h]] – hDDX19B residues 54-275 + ATP analog + RNA<BR />
**[[3ews]] - hDDX19B residues 54-275 + ADP<BR />
**[[5e7m]], [[5e7j]] – hDDX3X catalytic domain + nucleotide<br />
**[[3dkp]] – hDDX52 domain I + ADP<BR />
**[[2wax]], [[2way]] – hDDX6 C terminal + EDC3-FDF peptide<BR />
**[[2j0s]], [[2j0q]], [[2hyi]] – hDDX48 + protein mago nashi homolog + RNA-binding protein 8A + protein CASC3 + RNA<BR />
**[[2j0u]] - hDDX48 + protein CASC3<BR />
**[[2db3]] – DmVASA residues 200-623 + RNA – ''Drosophila melanogaster''<br />
**[[5nt7]] – DmVASA RecA-like domain + maternal effect protein<br />
**[[3nbf]] - TtHera N terminal (mutant) + 8-oxo-ADP<br />
**[[3nbf]] - TtHera N terminal (mutant) + 8-oxo-ADP<br />
**[[3moj]] - BsDBPA RNA-binding domain + RNA
**[[3moj]] - BsDBPA RNA-binding domain + RNA
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* DEAH box RNA helicase
* DEAH box RNA helicase


**[[2eqs]] – hDHX8 S1 domain<br />
**[[2eqs]] – hDHX8 S1 domain residues 260-355<br />
**[[3i4u]] – hDHX8 residues 950-1183<br />
**[[3i4u]] – hDHX8 residues 950-1183<br />
**[[3llm]] – hDHX9<br />
**[[3llm]] – hDHX9<br />
**[[2rs6]], [[2rs7]] – DHX9 RNA-binding domain – mouse – NMR<br />
**[[5xdr]] – hDHX15 residues 110-795 (mutant)<br />
**[[5xdr]] – hDHX15 residues 110-795 (mutant)<br />
**[[2n16]] – hDHX36 G-quadruplex domain - NMR<br />
**[[2n16]] – hDHX36 G-quadruplex domain - NMR<br />
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**[[5vhc]], [[5vhd]] – bDHX36 residues 150-1010 + ADP<br />
**[[5vhc]], [[5vhd]] – bDHX36 residues 150-1010 + ADP<br />
**[[5vhe]] – bDHX36 residues 56-1010 + DNA<br />
**[[5vhe]] – bDHX36 residues 56-1010 + DNA<br />
**[[2rs6]], [[2rs7]] – mDHX9 RNA-binding domain – NMR<br />


*ATP-dependent RNA helicase
*ATP-dependent RNA helicase


**[[2g9n]] - hEIF4A dead domain<br />
**[[6ro1]] - hDOB1 residues 70-1042 + NVL<br />
**[[2xzl]] – yNAM7 CH and helicase domains + RNA<BR />
**[[2xzl]] – yNAM7 CH and helicase domains + RNA<BR />
**[[2xgj]] – yDOB1 residues 81-1073 + RNA<BR />
**[[2xgj]] – yDOB1 residues 81-1073 + RNA<BR />
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**[[2fbv]], [[2fbx]], [[2fby]], [[2fc0]] - hWRN exonuclease domain + metal ion
**[[2fbv]], [[2fbx]], [[2fby]], [[2fc0]] - hWRN exonuclease domain + metal ion
**[[3aaf]] – hWRN C terminal + DNA<br />
**[[3aaf]] – hWRN C terminal + DNA<br />
**[[2e6l]], [[2e6m]]- WRN exonuclease domain - mouse
**[[2e6l]], [[2e6m]]- mWRN exonuclease domain  


*ATP-dependent DNA helicase Q
*ATP-dependent DNA helicase Q
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*ATP-dependent DNA helicase RecQ (Bloom Syndrome helicase)
*ATP-dependent DNA helicase RecQ (Bloom Syndrome helicase)


**[[4cgz]], [[4o3m]] - hRecQ catalytic domain + DNA<br />
**[[4cdg]] - hRecQ catalytic domain + nanobody<br />
**[[1d8b]] - yRecQ HRDC domain - NMR<BR />
**[[3iuo]] – RecQ residues 604-725 – ''Porphyromonas gingivalis''<BR />
**[[3iuo]] – RecQ residues 604-725 – ''Porphyromonas gingivalis''<BR />
**[[2rhf]] – DrRecQ HRDC domain 3 – ''Deinococcus radiodurans''<BR />
**[[2rhf]] – DrRecQ HRDC domain 3 – ''Deinococcus radiodurans''<BR />
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**[[1oyw]] - EcRecQ catalytic domain<BR />
**[[1oyw]] - EcRecQ catalytic domain<BR />
**[[1oyy]] - EcRecQ catalytic domain + ATP<BR />
**[[1oyy]] - EcRecQ catalytic domain + ATP<BR />
**[[1d8b]] - yRecQ HRDC domain - NMR<BR />
**[[4cgz]], [[4o3m]] - hRecQ catalytic domain + DNA<br />
**[[4cdg]] - hRecQ catalytic domain + nanobody<br />


*ATP-dependent DNA helicase RuvA, RuvB
*ATP-dependent DNA helicase RuvA, RuvB
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*Helicase BLM
*Helicase BLM


**[[5lup]] – hBLM DHBN domain <br />
**[[5lut]] – BLM DHBN domain - chicken<br />
**[[5lut]] – BLM DHBN domain - chicken<br />
**[[5lus]] – BLM DHBN domain - pelican<br />
**[[5lus]] – BLM DHBN domain - pelican<br />
**[[5lup]] – hBLM DHBN domain <br />


*Helicase CA8 or Prp28
*Helicase CA8 or Prp28
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*Helicase SKI2
*Helicase SKI2


**[[4a4k]] – ySKI2 insertion domain<br />
**[[4a4z]] – ySKI2 + AMPPNP<br />
**[[2va8]] – SsSKI2<br />
**[[2va8]] – SsSKI2<br />
**[[4a4k]] – ySKI2 insertion domain<br />
**[[4a4z]] – ySKI2 + AMPPNP


*Helicase SWR1
*Helicase SWR1
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