6i00: Difference between revisions
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==Cryo-EM informed directed evolution of Nitrilase 4 leads to a change in quaternary structure.== | |||
<StructureSection load='6i00' size='340' side='right'caption='[[6i00]], [[Resolution|resolution]] 3.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6i00]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I00 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I00 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i00 OCA], [http://pdbe.org/6i00 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i00 RCSB], [http://www.ebi.ac.uk/pdbsum/6i00 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i00 ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: Mulelu, A | == Function == | ||
[[Category: Woodward, J | [[http://www.uniprot.org/uniprot/NRL4_ARATH NRL4_ARATH]] Highly specific for beta-cyano-L-alanine (Ala(CN)). Low activity with 3-phenylpropionitrile (PPN) or allylcyanide and no activity with indole-3-acetonitrile. Not associated with auxin production but may be involved in cyanide detoxification.<ref>PMID:11060302</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mulelu, A E]] | |||
[[Category: Woodward, J D]] | |||
[[Category: Beta-cyano-l-alanine hydrolase]] | |||
[[Category: Cyanide detoxification]] | |||
[[Category: Helical filament]] | |||
[[Category: Hydrolase]] | |||
[[Category: Nitrilase]] | |||
Revision as of 06:09, 24 July 2019
Cryo-EM informed directed evolution of Nitrilase 4 leads to a change in quaternary structure.
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