6jmv: Difference between revisions
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==Crystal structure of the GluK3 ligand binding domain complex with SYM and zinc== | |||
<StructureSection load='6jmv' size='340' side='right'caption='[[6jmv]], [[Resolution|resolution]] 1.83Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6jmv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JMV FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SYM:2S,4R-4-METHYLGLUTAMATE'>SYM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6jfy|6jfy]], [[6jfz|6jfz]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jmv OCA], [http://pdbe.org/6jmv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jmv RCSB], [http://www.ebi.ac.uk/pdbsum/6jmv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jmv ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/GRIK3_RAT GRIK3_RAT]] Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.<ref>PMID:21907808</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Kumar, J]] | |||
[[Category: Kumari, J]] | |||
[[Category: Glutamate receptor]] | |||
[[Category: Kainate]] | |||
[[Category: Membrane protein]] | |||
[[Category: Sym]] | |||
Revision as of 06:13, 24 July 2019
Crystal structure of the GluK3 ligand binding domain complex with SYM and zinc
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