6pdm: Difference between revisions
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==Crystal structure of Human Protein Arginine Methyltransferase 9 (PRMT9)== | |||
<StructureSection load='6pdm' size='340' side='right'caption='[[6pdm]], [[Resolution|resolution]] 2.45Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6pdm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PDM FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_protein_arginine_methyltransferase Type II protein arginine methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.320 2.1.1.320] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pdm OCA], [http://pdbe.org/6pdm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pdm RCSB], [http://www.ebi.ac.uk/pdbsum/6pdm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pdm ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ANM9_HUMAN ANM9_HUMAN]] Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of SF3B2. Involved in the regulation of alternative splicing of pre-mRNA (PubMed:25737013, PubMed:25979344).<ref>PMID:25737013</ref> <ref>PMID:25979344</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Type II protein arginine methyltransferase]] | |||
[[Category: Arrowsmith, C H]] | |||
[[Category: Bountra, C]] | |||
[[Category: Edwards, A M]] | |||
[[Category: Halabelian, L]] | |||
[[Category: Hutchinson, A]] | [[Category: Hutchinson, A]] | ||
[[Category: | [[Category: Li, Y]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Seitova, A]] | [[Category: Seitova, A]] | ||
[[Category: | [[Category: Tempel, W]] | ||
[[Category: Zeng, H]] | [[Category: Zeng, H]] | ||
[[Category: | [[Category: Sgc]] | ||
[[Category: | [[Category: Transferase]] | ||
Revision as of 06:29, 31 July 2019
Crystal structure of Human Protein Arginine Methyltransferase 9 (PRMT9)
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