6pa0: Difference between revisions
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==Structure of the G77A mutant in Sodium Chloride== | |||
<StructureSection load='6pa0' size='340' side='right'caption='[[6pa0]], [[Resolution|resolution]] 2.05Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6pa0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PA0 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DGA:DIACYL+GLYCEROL'>DGA</scene>, <scene name='pdbligand=F09:NONAN-1-OL'>F09</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pa0 OCA], [http://pdbe.org/6pa0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pa0 RCSB], [http://www.ebi.ac.uk/pdbsum/6pa0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pa0 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI]] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Cuello, L G]] | |||
[[Category: Guan, L]] | [[Category: Guan, L]] | ||
[[Category: | [[Category: Kcsa]] | ||
[[Category: Permeation]] | |||
[[Category: Potassium channel]] | |||
[[Category: Protein transport]] | |||
[[Category: Protein transport-immune system complex]] | |||
[[Category: Selectivity]] | |||
Revision as of 06:00, 7 August 2019
Structure of the G77A mutant in Sodium Chloride
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