Response regulator: Difference between revisions
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<StructureSection load='1kgs' size='350' side='right' scene='' caption='Se-Met DNA-binding response regulator D complex with thiocyanate, [[1kgs]]'> | <StructureSection load='1kgs' size='350' side='right' scene='' caption='Se-Met DNA-binding response regulator D complex with thiocyanate, [[1kgs]]'> | ||
'''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments. | '''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments. | ||
Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal which is the signal receiving domain and C terminal which is the DNA-binding domain (DBD). | Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal which is the signal receiving domain and C terminal which is the DNA-binding domain (DBD). | ||
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**[[4ml3]], [[4mld]] – SpRR Rec domain (mutant)<br /> | **[[4ml3]], [[4mld]] – SpRR Rec domain (mutant)<br /> | ||
**[[4cbv]] – SpRR (mutant)<br /> | **[[4cbv]] – SpRR (mutant)<br /> | ||
**[[2a9o]], [[2a9p]], [[ | **[[2a9o]], [[2a9p]], [[6ebb]] – SpRR + Mn + BeF3<br /> | ||
**[[4zms]] ,[[4zmr]] - SpRR + Mg + BeF3<br /> | **[[4zms]] ,[[4zmr]] - SpRR + Mg + BeF3<br /> | ||
**[[2pln]] – HP1043 – ''Helicobacter pylori''<br /> | **[[2pln]] – HP1043 – ''Helicobacter pylori''<br /> | ||
