6q6c: Difference between revisions
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==Pore-modulating toxins exploit inherent slow inactivation to block K+ channels== | |||
<StructureSection load='6q6c' size='340' side='right'caption='[[6q6c]], [[Resolution|resolution]] 1.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6q6c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q6C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q6C FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q6c OCA], [http://pdbe.org/6q6c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q6c RCSB], [http://www.ebi.ac.uk/pdbsum/6q6c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q6c ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/VKTS1_CONST VKTS1_CONST]] Blocks specifically voltage-activated potassium channels (Kv) of the Shaker family (IC(50)=1.33 nM).<ref>PMID:15833744</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Dym, O]] | |||
[[Category: Fine, S]] | |||
[[Category: Frolow, F]] | |||
[[Category: Gordon, D]] | |||
[[Category: Gueta, H]] | |||
[[Category: Gurevitz, M]] | |||
[[Category: Hamer-Rogotner, S]] | |||
[[Category: Karbat, I]] | [[Category: Karbat, I]] | ||
[[Category: Panyi, G]] | [[Category: Panyi, G]] | ||
[[Category: | [[Category: Reuveny, E]] | ||
[[Category: Szanto, T]] | [[Category: Szanto, T]] | ||
[[Category: | [[Category: Toxin]] | ||
Revision as of 06:06, 21 August 2019
Pore-modulating toxins exploit inherent slow inactivation to block K+ channels
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