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| </StructureSection> | | </StructureSection> |
| ==3D structures of hydroxysteroid dehydrogenase==
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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| {{#tree:id=OrganizedByTopic|openlevels=0|
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| *3-α HSD or AKR1C2
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| '''For 3-α HSD type 2 see''' [[Prostaglandin F synthase]]
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| **[[1ral]] – rHSD – rat<BR />
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| **[[1fjh]] - CtHSD – ''Comamonas testosterone''<BR />
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| **[[4is2]] – CsHSD – ''Clostridium scindens''<br />
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| *''3-α HSD binary complex''
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| **[[2fvl]], [[2hdj]] - hHSD + NADP - human<BR />
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| **[[1lwi]] – rHSD + NADP<BR />
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| **[[1fk8]] – CtHSD + NAD<BR />
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| **[[2dkn]] - HSD + NAD – ''Pseudomonas''<BR />
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| **[[4is3]] - CsHSD + NAD<br />
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| *''3-α HSD ternary complex''
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| **[[4jq1]], [[4jq2]], [[4jq3]], [[4jq4]], [[4jqa]], [[4jtq]], [[4jtr]] - hHSD + NSAID drug + NADP <br />
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| **[[1afs]] - rHSD + hydroxysteroid + NADP<BR />
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| *3-α HSD type 3
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| **[[2hdj]] - hHSD + NADP<br />
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| **[[1ihi]], [[1j96]] - hHSD + hydroxysteroid + NADP <br />
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| **[[1xjb]] - hHSD + citrate+ acetate + NADP<br />
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| **[[4l1w]] - hHSD + progesterone + NADP<br />
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| **[[4l1x]] - hHSD (mutant) + progesterone + NADP<br />
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| **[[4xo6]], [[4xo7]] – hHSD + NADP + epiandrosterone derivative<br />
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| *7-α HSD
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| **[[3gaf]] - HSD – ''Brucella melitensis''<BR />
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| **[[1ahh]] – EcHSD + NAD – ''Escherichia coli''<BR />
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| **[[1ahi]], [[1fmc]] – EcHSD + hydroxysteroid + NAD
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| *20-α HSD or AKR1C1
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| **[[1q5m]] - raHSD + NADP – rabbit
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| *''20-α HSD ternary complex''
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| **[[1mrq]] – hHSD + hydroxysteroid + NADP<BR />
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| **[[4yvp]] – hHSD + NADP + sulfonylurea derivative<br />
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| **[[3c3u]], [[3nty]] - hHSD + inhibitor + NADP<BR />
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| **[[3gug]] - hHSD (mutant) + inhibitor + NADP<BR />
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| **[[1q13]] - raHSD + hydroxysteroid + NADP<BR />
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| *11-β HSD or corticosteroid 11-β-dehydrogenase 1
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| **[[1xu7]], [[1xu9]] - hHSD (mutant) + NADP<BR />
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| **[[2pd6]] - hHSD + NAD<BR />
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| **[[3hb4]] - hHSD + inhibitor<BR />
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| **[[3dey]] - hHSD + hydroxysteroid<BR />
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| **[[1y5m]] - mHSD + NADP - mouse<BR />
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| **[[1xse]] - gpHSD catalytic domain + NADP – guinea pig<BR />
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| **[[3dwf]], [[3lz6]] - gpHSD catalytic domain (mutant) + NADP<BR />
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| *''11-β HSD ternary complex''
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| **[[2bel]] - hHSD 1 + hydroxysteroid + NADP<BR />
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| **[[2irw]], [[2ilt]], [[4bb5]], [[4bb6]] - hHSD 1 + inhibitor + NADP<BR />
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| **[[2rbe]], [[3byz]], [[3bzu]], [[3ch6]], [[3czr]], [[3d3e]], [[3d4n]], [[3d5q]], [[3ey4]], [[3frj]], [[3hfg]], [[3fco]], [[3h6k]], [[3oq1]], [[3pdj]], [[3tfq]], [[3qqp]], [[4c7j]], [[4c7k]], [[4p38]], [[5pgu]], [[5pgv]], [[5pgw]], [[5pgx]], [[5pgy]], [[5pgz]], [[5pii]], [[5pij]] - hHSD 1 (mutant) + inhibitor + NADP<BR />
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| **[[6nj7]] - hHSD 1 + colleic acid + NAP<br />
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| **[[3g49]] - gpHSD catalytic domain + inhibitor + NADP<BR />
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| **[[1y5r]], [[3gmd]] - mHSD 1 + hydroxysteroid + NADP<BR />
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| **[[4k26]] - mHSD 1 + inhibitor + NADP<br />
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| **[[4nmh]] - mHSD 1 (mutant) + inhibitor + NADP<br />
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| *17-α HSD or AKR1C21
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| **[[2he8]] – mHSD - mouse <br />
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| **[[3fjn]] - mHSD (mutant) <br />
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| **[[2p5n]], [[2he5]], [[2hej]] - mHSD + NADP <br />
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| **[[2ipf]] - mHSD + hydroxysteroid + NADP <br />
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| **[[2ipg]], [[2ipj]] - mHSD (mutant) + hydroxysteroid + NADP<br />
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| **[[3cv6]] - mHSD (mutant) + inhibitor + NADP<br />
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| *17-β HSD or estradiol 11-β-dehydrogenase 1
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| '''For 17-β HSD type 5 or AKR1C3 see''' [[Prostaglandin F synthase]]
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| **[[1bhs]] – hHSD 1 <BR />
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| **[[1s9c]] - hHSD 4 (mutant) <BR />
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| **[[5ics]] – hHSD 14 <BR />
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| **[[3is3]] – ClHSD – ''Cochliobolus lunatus''<BR />
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| **[[3itd]] - ClHSD (mutant)
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| *''17-β HSD binary complex''
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| **[[1jtv]], [[1yb1]], [[3dhe]], [[1fds]], [[1iol]], [[3klm]], [[3klp]], [[3km0]] - hHSD + hydroxysteroid<br />
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| **[[1fdw]], [[1dht]] - hHSD (mutant) + hydroxysteroid<BR />
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| **[[6mnc]] – hHSD 1 + estrone<br />
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| **[[1fdv]] - hHSD 1 (mutant) + NAD<BR />
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| **[[1qyv]] - hHSD 1 + NADP<BR />
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| **[[1i5r]], [[6dtp]] - hHSD 1 + inhibitor<br />
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| **[[1zbq]] - hHSD 4 + NAD<BR />
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| **[[5l7t]], [[5l7w]], [[5l7y]], [[5icm]], [[5en4]] - hHSD 14 + inhibitor<br />
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| **[[6h0m]], [[6hno]], [[5js6]], [[5jsf]] - hHSD 14 (mutant) + NAD<br />
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| **[[3qwf]] - ClHSD + NADP<BR />
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| **[[4fj0]], [[4fj1]], [[4fj2]], [[4fiz]] – ClHSD + dehydroxy flavonoid inhibitor<br />
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| *''17-β HSD ternary complex''
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| **[[1qyw]], [[1qyx]], [[1fdt]] - hHSD 1 + hydroxysteroid + NADP<BR />
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| **[[1a27]], [[1fdu]] - hHSD 1 (mutant) + hydroxysteroid + NADP<BR />
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| **[[3hb5]], [[6cge]] - hHSD 1 + inhibitor + NADP<BR />
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| **[[4hfr]], [[4hx5]], [[4iju]], [[4ijv]], [[4ijw]], [[4k1l]], [[6cgc]] - hHSD 1 (mutant) + inhibitor + NADP<br />
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| **[[6mne]] – hHSD 1 + NADP + estrone<br />
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| **[[5o42]], [[5o43]], [[5o6o]], [[5o6x]], [[5o6z]], [[5o72]] - hHSD 14 + inhibitor + NAD<br />
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| **[[5hs6]] - hHSD + NAD + estrone<br />
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| **[[4cql]] - hHSD 8 + carbonyl reductase + NAD<br />
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| **[[4cqm]] - hHSD 8 + carbonyl reductase + NADP<br />
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| **[[5o42]], [[5o43]], [[5o6o]], [[5o6x]], [[5o6z]], [[5o72]] - hHSD 14 + inhibitor + NAD<br />
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| **[[6ffb]], [[6g4l]], [[6gtu]], [[5o7c]] - hHSD 14 (mutant) + inhibitor + NAD<br />
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| **[[6emm]] - hHSD 14 (mutant) + salicilate + NAD<br />
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| **[[5hs6]] - hHSD 14 + NAD + estrone<br />
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| **[[3qwi]], [[3qwh]] - ClHSD + hydroxysteroid + NADP<BR />
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| *3-α 20-β HSD
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| **[[2hsd]] – SeHSD – ''Streptomyces exfoliates''<BR />
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| **[[1hdc]] – SeHSD + inhibitor
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| *Carbonyl reductase/20-β HSD
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| **[[1n5d]] - HSD + NADP – pig<br />
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| *3-β/17-β HSD
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| **[[1hxh ]] - CtHSD
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| }}
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| == References == | | == References == |
| <references/> | | <references/> |
| [[Category:Topic Page]] | | [[Category:Topic Page]] |
