6e24: Difference between revisions
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==Ternary structure of c-Myc-TBP-TAF1== | |||
<StructureSection load='6e24' size='340' side='right'caption='[[6e24]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6e24]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E24 FirstGlance]. <br> | |||
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e24 OCA], [http://pdbe.org/6e24 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e24 RCSB], [http://www.ebi.ac.uk/pdbsum/6e24 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e24 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/TAF1_YEAST TAF1_YEAST]] Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.<ref>PMID:8980232</ref> <ref>PMID:10788514</ref> <ref>PMID:12138208</ref> <ref>PMID:12516863</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Histone acetyltransferase]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith, C H]] | |||
[[Category: Dong, A]] | |||
[[Category: Edwards, A M]] | |||
[[Category: Penn, L]] | |||
[[Category: Structural genomic]] | |||
[[Category: Sunnerhagen, M]] | |||
[[Category: Tong, Y]] | |||
[[Category: Wei, Y]] | |||
[[Category: Carcinogenesis]] | |||
[[Category: Dna binding protein]] | |||
[[Category: Transcriptional regulation]] | |||
Revision as of 10:17, 2 October 2019
Ternary structure of c-Myc-TBP-TAF1
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