RNA Polymerase II: Difference between revisions

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Once the PIC is formed, RNAP II initiates RNA synthesis and produces a short transcript. When RNAP II becomes phosphorylated, it releases some of the GTFs from the complex and moves away from the promoter. TFIID stays bound to the promoter and can reinitiate transcription. The transcription factors are replaced by a new six-protein complex call the Elongator. TFIIF and TFIIH both remain associated with RNAP II during elongation.  
Once the PIC is formed, RNAP II initiates RNA synthesis and produces a short transcript. When RNAP II becomes phosphorylated, it releases some of the GTFs from the complex and moves away from the promoter. TFIID stays bound to the promoter and can reinitiate transcription. The transcription factors are replaced by a new six-protein complex call the Elongator. TFIIF and TFIIH both remain associated with RNAP II during elongation.  


<scene name='82/824648/Tfiid-tbp/1'>TFIID/TBP</scene>
<scene name='82/824648/Tfiib/1'>TFIIB</scene>
<scene name='82/824648/Tfiia/1'>TFIIA</scene>
<scene name='82/824648/Tfiif/1'>TFIIF</scene>
<scene name='82/824648/Tfiie/1'>TFIIE</scene>
<scene name='82/824648/Tfiih/1'>TFIIH</scene>




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