6jv9: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6jv9 is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal Structure of Human CRMP2 1-532, unmodified==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6jv9]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JV9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JV9 FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jv9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jv9 OCA], [http://pdbe.org/6jv9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jv9 RCSB], [http://www.ebi.ac.uk/pdbsum/6jv9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jv9 ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/DPYL2_HUMAN DPYL2_HUMAN]] Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (By similarity). Plays a role in neuron projection morphogenesis.<ref>PMID:11477421</ref> <ref>PMID:15466863</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Hirokawa, N]]

[[Category: Jiang, X]]

[[Category: Ogawa, T]]

[[Category: Gap activity]]

[[Category: Microtubule associated protein]]

[[Category: Neuronal protein]]

[[Category: Structural protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6jv9 is ON HOLD  until Paper Publication
+==Crystal Structure of Human CRMP2 1-532, unmodified==
+<StructureSection load='6jv9' size='340' side='right'caption='[[6jv9]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6jv9]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JV9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JV9 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jv9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jv9 OCA], [http://pdbe.org/6jv9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jv9 RCSB], [http://www.ebi.ac.uk/pdbsum/6jv9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jv9 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/DPYL2_HUMAN DPYL2_HUMAN]] Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (By similarity). Plays a role in neuron projection morphogenesis.<ref>PMID:11477421</ref> <ref>PMID:15466863</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Hirokawa, N]]
+[[Category: Jiang, X]]
+[[Category: Ogawa, T]]
+[[Category: Gap activity]]
+[[Category: Microtubule associated protein]]
+[[Category: Neuronal protein]]
+[[Category: Structural protein]]