6iue: Difference between revisions
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==DNA helical wire containing Hg(II)== | |||
<StructureSection load='6iue' size='340' side='right'caption='[[6iue]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6iue]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IUE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IUE FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6iue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iue OCA], [http://pdbe.org/6iue PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iue RCSB], [http://www.ebi.ac.uk/pdbsum/6iue PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iue ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Numerous applications of metal ion-mediated base pairs (metallo-base pairs) to nucleic acid-based nanodevices and genetic code expansion have extensively been studied. Many of these metallo-base pairs are formed in DNA and RNA duplexes containing Watson-Crick base pairs. Recently, a crystal structure of a metal-DNA nanowires with uninterrupted one-dimensional silver array has been reported. Herein, we have determined a crystal structure of a novel DNA helical wire containing Hg(II)-mediated T:T and T:G base pairs and water-mediated C:C base pairs. The Hg-DNA wire contains no Watson-Crick base pair. The crystals of the Hg-DNA wire, the first DNA wire structure driven by Hg(II) ions, were obtained by mixing a short oligonucleotide d(TTTGC) and Hg(II) ions. This study demonstrates potentials of metallo-DNA to form various structural components which can be used for functional nanodevices. | |||
Novel DNA helical wire containing Hg(II) mediated T:T and T:G pairs.,Ono A, Kanazawa H, Ito H, Goto M, Nakamura K, Saneyoshi H, Kondo J Angew Chem Int Ed Engl. 2019 Sep 10. doi: 10.1002/anie.201910029. PMID:31507027<ref>PMID:31507027</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
<div class="pdbe-citations 6iue" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Goto, M]] | |||
[[Category: Ito, H]] | |||
[[Category: Kanazawa, H]] | |||
[[Category: Kondo, J]] | [[Category: Kondo, J]] | ||
[[Category: Nakamura, K]] | |||
[[Category: Ono, A]] | [[Category: Ono, A]] | ||
[[Category: Saneyoshi, H]] | [[Category: Saneyoshi, H]] | ||
[[Category: | [[Category: Dna]] | ||
[[Category: Mercury]] | |||
[[Category: Metallo-base pair]] | |||
[[Category: Nanowire]] | |||
Revision as of 05:50, 16 October 2019
DNA helical wire containing Hg(II)
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