Virion infectivity factor: Difference between revisions
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== Function == | == Function == | ||
'''Virion infectivity factor''' (Vif) of HIV-1 is essential for efficient viral replication by binding to the a component of the innate immune system and triggering its polyubiquitination and rapid degradation thus preventing its entry into progeny virions<ref>PMID:15177194</ref>. <scene name='75/750233/Cv/ | '''Virion infectivity factor''' (Vif) of HIV-1 is essential for efficient viral replication by binding to the a component of the innate immune system and triggering its polyubiquitination and rapid degradation thus preventing its entry into progeny virions<ref>PMID:15177194</ref>. <scene name='75/750233/Cv/4'>Interactions between HIV-1 virion infectivity factor and human elongin-B and elongin-C</scene>. | ||
For details see [[HIV and accessory proteins]] | For details see [[HIV and accessory proteins]] | ||
Revision as of 12:47, 17 October 2019
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3D Structures of virion infectivity factor
Updated on 17-October-2019
HIV and accessory proteins – Vif + cullin-5 + elongin-C + elongin-B + CBF-β – HIV-1
2ma9, 3dcg – Vif + elongin-C + elongin-B – HIV-1