6kkt: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6kkt is ~~ON HOLD until Paper Publication~~

==human KCC1 structure determined in KCl and lipid nanodisc==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6kkt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KKT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KKT FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DU0:2-[2-[(1~{S},2~{S},4~{S},5~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2-oxane]-16-yl]oxyethyl]propane-1,3-diol'>DU0</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6kkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kkt OCA], [http://pdbe.org/6kkt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kkt RCSB], [http://www.ebi.ac.uk/pdbsum/6kkt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kkt ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/S12A4_HUMAN S12A4_HUMAN]] Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity.

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Bai, X]]

[[Category: Chang, S]]

[[Category: Guo, J]]

[[Category: Liu, S]]

[[Category: Ye, S]]

[[Category: Ion co-transporter]]

[[Category: Transport protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6kkt is ON HOLD  until Paper Publication
+==human KCC1 structure determined in KCl and lipid nanodisc==
+<StructureSection load='6kkt' size='340' side='right'caption='[[6kkt]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6kkt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KKT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KKT FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DU0:2-[2-[(1~{S},2~{S},4~{S},5~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2-oxane]-16-yl]oxyethyl]propane-1,3-diol'>DU0</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6kkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kkt OCA], [http://pdbe.org/6kkt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kkt RCSB], [http://www.ebi.ac.uk/pdbsum/6kkt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kkt ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/S12A4_HUMAN S12A4_HUMAN]] Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Bai, X]]
+[[Category: Chang, S]]
+[[Category: Guo, J]]
+[[Category: Liu, S]]
+[[Category: Ye, S]]
+[[Category: Ion co-transporter]]
+[[Category: Transport protein]]