MtrF: Difference between revisions
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< | <StructureSection load='3pmq' size='400' side='right' scene='' caption=''MtrF General Structure containing 10 heme groups, pdb:[[3pmq]]''> | ||
[[MtrF]] is a cell surface cytochrome on the Gram-negative bacteria known as ''Shewanella oneidensis''.<ref name="mtrf"> PMID:11418600</ref> MtrF is involved with shuttling electrons across its (''S. oneidensis'') outer surface. MtrF has several homologues, MtrC and the protein OmcA. These three different proteins are thought to be replaceable with one another in deletion mutation experiments.<ref name= "mtrf" /> | [[MtrF]] is a cell surface cytochrome on the Gram-negative bacteria known as ''Shewanella oneidensis''.<ref name="mtrf"> PMID:11418600</ref> MtrF is involved with shuttling electrons across its (''S. oneidensis'') outer surface. MtrF has several homologues, MtrC and the protein OmcA. These three different proteins are thought to be replaceable with one another in deletion mutation experiments.<ref name= "mtrf" /> | ||
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A prime example of MtrF regulation is the study of "Regulation of MtrF Expression in ''Neisseria gonorrhoeae'' and Its Role in High-Level Antimicrobial Resistance".<ref> PMID:15901695 </ref> In this study the expression of MtrF was repressed by MtrR (the major repressor in the mtrCDE expression). Another repressor known as MpeR can also regulate the expression of MtrF. Repression of MtrF by MtrR and MpeR was used, demonstrating that the repressive effects mediated by these regulators are independent processes. MtrF was also disabled and the significant reduction in the induction of hydrophobic agent resistance and it was found that the expression of MtrF is enhanced when ''Gonococci'' are grown under inducing conditions. | A prime example of MtrF regulation is the study of "Regulation of MtrF Expression in ''Neisseria gonorrhoeae'' and Its Role in High-Level Antimicrobial Resistance".<ref> PMID:15901695 </ref> In this study the expression of MtrF was repressed by MtrR (the major repressor in the mtrCDE expression). Another repressor known as MpeR can also regulate the expression of MtrF. Repression of MtrF by MtrR and MpeR was used, demonstrating that the repressive effects mediated by these regulators are independent processes. MtrF was also disabled and the significant reduction in the induction of hydrophobic agent resistance and it was found that the expression of MtrF is enhanced when ''Gonococci'' are grown under inducing conditions. | ||
</StructureSection> | |||
==3D Structures of Cytochrome C== | ==3D Structures of Cytochrome C== | ||
[[Cytochrome c]] | [[Cytochrome c]] | ||
