6o6w: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6o6w is ~~ON HOLD~~ ~~until Paper Publication~~

==Solution structure of human myeloid-derived growth factor==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6o6w]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O6W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6O6W FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6o6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o6w OCA], [http://pdbe.org/6o6w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6o6w RCSB], [http://www.ebi.ac.uk/pdbsum/6o6w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6o6w ProSAT]</span></td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/MYDGF_HUMAN MYDGF_HUMAN]] Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis (PubMed:25581518).[UniProtKB:Q9CPT4]<ref>PMID:25581518</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Bortnov, V]]

[[Category: Lee, W]]

[[Category: Markley, J L]]

[[Category: Mosher, D F]]

[[Category: Tonelli, M]]

[[Category: Endoplasmic reticulum]]

[[Category: Unknown function]]

[[Category: Upf0556]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6o6w is ON HOLD  until Paper Publication
+==Solution structure of human myeloid-derived growth factor==
+<StructureSection load='6o6w' size='340' side='right'caption='[[6o6w]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6o6w]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O6W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6O6W FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6o6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o6w OCA], [http://pdbe.org/6o6w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6o6w RCSB], [http://www.ebi.ac.uk/pdbsum/6o6w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6o6w ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/MYDGF_HUMAN MYDGF_HUMAN]] Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis (PubMed:25581518).[UniProtKB:Q9CPT4]<ref>PMID:25581518</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Bortnov, V]]
+[[Category: Lee, W]]
+[[Category: Markley, J L]]
+[[Category: Mosher, D F]]
+[[Category: Tonelli, M]]
+[[Category: Endoplasmic reticulum]]
+[[Category: Unknown function]]
+[[Category: Upf0556]]