Peroxiredoxin: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
In the typical 2-cysteine Prx the <scene name='43/433646/Cv/5'>Cys-Cys bond is formed between two subunits</scene><ref>PMID:10535922</ref>. <scene name='43/433646/Cv/6'>Cl coordination site</scene>. Water molecules is shown as red sphere. | In the typical 2-cysteine Prx the <scene name='43/433646/Cv/5'>Cys-Cys bond is formed between two subunits</scene><ref>PMID:10535922</ref>. <scene name='43/433646/Cv/6'>Cl coordination site</scene>. Water molecules is shown as red sphere. | ||
== 3D Structures of Peroxiredoxin == | |||
[[Peroxiredoxin 3D structures]] | |||
</StructureSection> | </StructureSection> | ||
== 3D Structures of Peroxiredoxin == | == 3D Structures of Peroxiredoxin == | ||
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*Peroxiredoxin | *Peroxiredoxin | ||
**[[1qmv]] - h2Cys-Prx – human<br /> | |||
**[[1qq2]] – r2Cys-Prx – rat<br /> | **[[1qq2]] – r2Cys-Prx – rat<br /> | ||
**[[2a4v]] – yPrx dot5 C-terminal (mutant) – yeast<br /> | **[[2a4v]] – yPrx dot5 C-terminal (mutant) – yeast<br /> | ||
**[[3cmi]] – yPrx hyr1 - yeast<br /> | **[[3cmi]] – yPrx hyr1 - yeast<br /> | ||
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**[[3ixr]] – Prx PRXQ (mutant) – ''Xylella fastidiosa''<br /> | **[[3ixr]] – Prx PRXQ (mutant) – ''Xylella fastidiosa''<br /> | ||
**[[5epf]] - Prx – ''Mycobacterium tuberculosis''<br /> | **[[5epf]] - Prx – ''Mycobacterium tuberculosis''<br /> | ||
**[[2c0d]] – Pf2Cys-Prx – ''Plasmodium falciparum''<br /> | |||
**[[1xiy]] – Pf1Cys-Prx<br /> | |||
**[[1xcc]], [[2h01]], [[3tb2]] - 1Cys-Prx – ''Plasmodium yoelii''<br /> | |||
**[[2i81]] - 2Cys-Prx – ''Plasmodium vivax''<br /> | |||
**[[6itz]] - TkPrx – ''Thermococcus kodakarensis''<br /> | |||
**[[6iu0]], [[6iu1]] – TkPrx (mutant) <br /> | |||
**[[6e0f]], [[6e0g]] – 2Cys-Prx – ''Leishmania infantum''<br /> | |||
**[[5zte]] – 2Cys-Prx (mutant) – ''Arabidopsis thaliana''<br /> | |||
**[[5ovq]] - Prx – ''Aquifex aeolicus''<br /> | |||
*Peroxiredoxin 1 | *Peroxiredoxin 1 | ||
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**[[2rii]], [[3hy2]] – hPrx 1 (mutant)+sulfiredoxin 1<br /> | **[[2rii]], [[3hy2]] – hPrx 1 (mutant)+sulfiredoxin 1<br /> | ||
**[[2z9s]] – rPrx 1 (mutant) <br /> | **[[2z9s]] – rPrx 1 (mutant) <br /> | ||
**[[3zl5]] - mPrx 1 (mutant) – mouse<br /> | |||
**[[5ykj]] – y1Cys-Prx<br /> | |||
**[[4kw6]], [[4fh8]] – Prx 1 – ''Ancylostoma ceylanicum''<br /> | **[[4kw6]], [[4fh8]] – Prx 1 – ''Ancylostoma ceylanicum''<br /> | ||
*Peroxiredoxin 2 | *Peroxiredoxin 2 | ||
**[[ | **[[5ijt]] – hPrx II <br /> | ||
**[[2pwj]] – Prx II – garden pea<br /> | **[[2pwj]] – Prx II – garden pea<br /> | ||
**[[4dsq]], [[4dsr]], [[4h86]], [[4owy]] – yPrx II<br /> | **[[4dsq]], [[4dsr]], [[4h86]], [[4owy]] – yPrx II<br /> | ||
**[[4dss]] – yPrx II (mutant) + thioredoxin II<br /> | **[[4dss]] – yPrx II (mutant) + thioredoxin II<br /> | ||
**[[ | **[[1tp9]] – Prx II – ''Populus trichocarpa''<br /> | ||
*Peroxiredoxin 3 | *Peroxiredoxin 3 | ||
**[[1zye]] – Prx III (mutant) – bovine<br /> | **[[1zye]] – Prx III (mutant) – bovine<br /> | ||
**[[5ykw]] - yPrx III (mutant) + peptide<br /> | |||
**[[5k1g]], [[5k2i]] - VvPrx III (mutant) – ''Vibrio vulnificus''<br /> | **[[5k1g]], [[5k2i]] - VvPrx III (mutant) – ''Vibrio vulnificus''<br /> | ||
**[[5k2j]] - VvPrx III (mutant) + H2O2<br /> | **[[5k2j]] - VvPrx III (mutant) + H2O2<br /> | ||
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**[[5hqp]] - hPrx 4 (mutant) + ERP44<br /> | **[[5hqp]] - hPrx 4 (mutant) + ERP44<br /> | ||
**[[4rqx]] – hPrx 4 + thioethanesulfonic acid<br /> | **[[4rqx]] – hPrx 4 + thioethanesulfonic acid<br /> | ||
**[[2pn8]], [[3tjb]], [[3tkp]], [[3tkq]], [[3tks]] – hPrx 4<br /> | **[[2pn8]], [[3tjb]], [[3tkp]], [[3tkq]], [[3tks]] – hPrx 4<br /> | ||
**[[3vwu]], [[3vwv]] - mPrx 4 (mutant) <br /> | **[[3vwu]], [[3vwv]] - mPrx 4 (mutant) <br /> | ||
**[[3qpm]] – Prx 4 – ''Larimichtys crocea''<br /> | |||
*Peroxiredoxin 5 | *Peroxiredoxin 5 | ||
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*Peroxiredoxin 6 | *Peroxiredoxin 6 | ||
**[[5b6m]], [[5b6n]] - hPrx 6<br /> | |||
**[[2v2g]] – lPrx 6 <br /> | **[[2v2g]] – lPrx 6 <br /> | ||
**[[2v32]], [[2v41]] – lPrx 6 (mutant)<br /> | **[[2v32]], [[2v41]] – lPrx 6 (mutant)<br /> | ||
*Peroxiredoxin Asp F3 | *Peroxiredoxin Asp F3 | ||
