6n2u: Difference between revisions
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==IL-8 Structure from Bacterial Expression Source== | |||
<StructureSection load='6n2u' size='340' side='right'caption='[[6n2u]], [[Resolution|resolution]] 1.25Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6n2u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N2U FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n2u OCA], [http://pdbe.org/6n2u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n2u RCSB], [http://www.ebi.ac.uk/pdbsum/6n2u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n2u ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: Luo, J | == Function == | ||
[[http://www.uniprot.org/uniprot/IL8_HUMAN IL8_HUMAN]] IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.<ref>PMID:2145175</ref> <ref>PMID:2212672</ref> <ref>PMID:11978786</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Jung, J H]] | |||
[[Category: Luo, J L]] | |||
[[Category: Park, H]] | [[Category: Park, H]] | ||
[[Category: | [[Category: Il-8]] | ||
[[Category: Immune system]] | |||
Revision as of 15:25, 20 November 2019
IL-8 Structure from Bacterial Expression Source
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