6pz2: Difference between revisions
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==Crystal Structure of FolP (dihydropteroate synthase) from Colstridium difficile in the presence of pteroic acid== | |||
<StructureSection load='6pz2' size='340' side='right'caption='[[6pz2]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6pz2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PZ2 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=PT1:PTEROIC+ACID'>PT1</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropteroate_synthase Dihydropteroate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.15 2.5.1.15] </span></td></tr> | ||
[[Category: Girardi, N | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pz2 OCA], [http://pdbe.org/6pz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pz2 RCSB], [http://www.ebi.ac.uk/pdbsum/6pz2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pz2 ProSAT]</span></td></tr> | ||
[[Category: Thoden, J | </table> | ||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/A0A160WS51_CLODI A0A160WS51_CLODI]] Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.[RuleBase:RU361205] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Dihydropteroate synthase]] | |||
[[Category: Large Structures]] | |||
[[Category: Girardi, N M]] | |||
[[Category: Holden, H M]] | |||
[[Category: Thoden, J B]] | |||
[[Category: Antibiotic resistance]] | |||
[[Category: Clostridium]] | |||
[[Category: Dhp]] | |||
[[Category: Transferase]] | |||
Revision as of 06:54, 27 November 2019
Crystal Structure of FolP (dihydropteroate synthase) from Colstridium difficile in the presence of pteroic acid
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