Potassium Channel: Difference between revisions

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Michal Harel (talk | contribs)
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Michal Harel (talk | contribs)
32,820 edits
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Line 47: Line 47:
**[[3eau]] - rKCh β-2 +cortisone<br />
**[[3eau]] - rKCh β-2 +cortisone<br />
**[[3eb3]], [[3eb4]] - rKCh β-2 (mutant) + cortisone<br />
**[[3eb3]], [[3eb4]] - rKCh β-2 (mutant) + cortisone<br />
**[[6ci1]] - rKCh β-2.1 – Cryo EM<br />
**[[4hoi]] – mKCh Kv10.1 PAS domain – mouse<br />
**[[4hoi]] – mKCh Kv10.1 PAS domain – mouse<br />
**[[4llo]] – mKCh EAG1 <br />
**[[4llo]] – mKCh EAG1 <br />
Line 53: Line 54:
**[[2k44]] – KCh voltage-sensor paddle domain – NMR<br />
**[[2k44]] – KCh voltage-sensor paddle domain – NMR<br />
**[[3e86]], [[3e83]] – BcKCh transmembrane domain – ''Bacillus cereus''<br />
**[[3e86]], [[3e83]] – BcKCh transmembrane domain – ''Bacillus cereus''<br />
**[[3e8g]], [[3e89]], [[3e8b]], [[3e8f]], [[3e8h]] – BcKCh transmembrane domain +ions<br />
**[[3e8g]], [[3e89]], [[3e8b]], [[3e8f]], [[3e8h]], [[6dz1]], [[6cpv]] – BcKCh transmembrane domain +ions<br />
**[[4r8c]], [[4r50]], [[2ahz]], [[2ahy]], [[4rai]], [[2q67]], [[2q68]], [[2q69]], [[2q6a]], [[3ouf]], [[4pdv]], [[4pdr]], [[4pdl]], [[4pdm]], [[4ro2]], [[4r7c]], [[4r6z]] – BcKCh (mutant) + ion<br />
**[[4r8c]], [[4r50]], [[2ahz]], [[2ahy]], [[4rai]], [[2q67]], [[2q68]], [[2q69]], [[2q6a]], [[3ouf]], [[4pdv]], [[4pdr]], [[4pdl]], [[4pdm]], [[4ro2]], [[4r7c]], [[4r6z]] – BcKCh transmembrane domain (mutant) + ion<br />
**[[4pdv]], [[4pdr]], [[4pdl]], [[4pdm]] – BcKCh (mutant)<br />
**[[4pdv]], [[4pdr]], [[4pdl]], [[4pdm]] – BcKCh (mutant)<br />
**[[1bl8]], [[1f6g]] - SlKCh Kcsa (mutant) - ''Streptomyces lividans''<br />
**[[1bl8]], [[1f6g]] - SlKCh Kcsa (mutant) - ''Streptomyces lividans''<br />
Line 82: Line 83:
**[[3lnm]], [[6ebl]], [[6ebk]] - rKCh Kv2.1/KCh Kv1.2 (mutant)<br />
**[[3lnm]], [[6ebl]], [[6ebk]] - rKCh Kv2.1/KCh Kv1.2 (mutant)<br />
**[[5k7l]] - rKCh EAG1 + calmodulin  <br />
**[[5k7l]] - rKCh EAG1 + calmodulin  <br />
**[[6pbx]], [[6pby]] - rKCh EAG1 + calmodulin – Cryo EM <br />
**[[3eff]] - mKCh + FAB <br />
**[[3eff]] - mKCh + FAB <br />
**[[2w0f]] - mKCh + FAB + tetraoctylammonium<br />
**[[2w0f]] - mKCh + FAB + tetraoctylammonium<br />
Line 88: Line 90:
**[[3f5w]], [[1zwi]], [[2hjf]] - mKCh (mutant) + antibody heavy+light chains<br />
**[[3f5w]], [[1zwi]], [[2hjf]] - mKCh (mutant) + antibody heavy+light chains<br />
**[[5vms]] - KCh Kv7.1 + calmodulin - frog <br />
**[[5vms]] - KCh Kv7.1 + calmodulin - frog <br />
**[[1k4c]], [[1k4d]], [[4lcu]], [[5ec2]], [[5ec1]], [[5ebw]], [[5ebm]], [[5ebl]], [[5e1a]], [[4lbe]] - SlKCh Kcsa (mutant) + antibody <br />
**[[3pjs]], [[5j9p]], [[4uuj]], [[4msw]], [[5vkh]], [[5vke]], [[5vk6]]  – SlKCh Kcsa + antibody<br />
**[[3pjs]], [[5j9p]], [[4uuj]], [[4msw]], [[4lbe]], [[5vkh]], [[5vke]], [[5vk6]] – SlKCh Kcsa + antibody<br />
**[[1k4c]], [[1k4d]], [[4lcu]], [[5ec2]], [[5ec1]], [[5ebw]], [[5ebm]], [[5ebl]], [[5e1a]], [[4lbe]], [[6pa0]], [[6nfu]], [[6nfv]] - SlKCh Kcsa (mutant) + antibody <br />
**[[2a9h]] - SlKCh Kcsa (mutant) + charybdotoxin<br />
**[[2a9h]] - SlKCh Kcsa (mutant) + charybdotoxin<br />
**[[6by2]], [[6by3]] - KCh Kcsa (mutant) + antibody – ''Streptomyces coelicolor''<br />
**[[2a0l]] - AeKCh + FV<br />
**[[2a0l]] - AeKCh + FV<br />
**[[1orq]] - AeKCh (mutant) + FAB<br />
**[[1orq]] - AeKCh (mutant) + FAB<br />
Line 116: Line 119:
**[[4umo]] - hKCh Kv7.1 (mutant) + calmodulin  <br />
**[[4umo]] - hKCh Kv7.1 (mutant) + calmodulin  <br />
**[[5j03]], [[6feh]], [[6feg]] - hKCh Kv7.2 + calmodulin  <br />
**[[5j03]], [[6feh]], [[6feg]] - hKCh Kv7.2 + calmodulin  <br />
**[[6b8p]], [[6b8n]], [[6b8m]], [[6b8l]] - hKCh Kv7.4 + calmodulin  <br />
**[[6b8p]], [[6b8n]], [[6b8m]], [[6b8l]], [[6n5w]] - hKCh Kv7.4 + calmodulin  <br />
**[[6b8q]] - hKCh Kv7.5 + calmodulin  <br />
**[[6b8q]] - hKCh Kv7.5 + calmodulin  <br />
**[[6rv2]] - hKCh TASK-1  <br />
**[[6rv3]], [[6rv4]] - hKCh TASK-1 + inhibitor <br />


*Inward rectifier KCh
*Inward rectifier KCh


**[[6c3p]], [[6c3o]] - hIRK 11 + sulfonylurea receptor + ATP + ADP – Cryo EM<br />
**[[6c3p]], [[6c3o]] - hIRK 11 + SUR1 + ATP + ADP – Cryo EM<br />
**[[6baa]] - hIRK 11 + sulfonylurea receptor + ATP + glibenclamide – Cryo EM<br />
**[[6baa]] - hIRK 11 + SUR1 + ATP + diabetes drug – Cryo EM<br />
**[[3ukm]] – hIRK TWIK-1<br />
**[[3ukm]] – hIRK TWIK-1<br />
**[[3um7]] – hIRK TRAAK<br />
**[[3um7]] – hIRK TRAAK<br />
Line 128: Line 133:
**[[4wfh]], [[4wfg]], [[4wfe]], [[4wff]] - hIRK TRAAK + antibody<br />
**[[4wfh]], [[4wfg]], [[4wfe]], [[4wff]] - hIRK TRAAK + antibody<br />
**[[4i9w]] - hIRK TRAAK (mutant) + antibody<br />
**[[4i9w]] - hIRK TRAAK (mutant) + antibody<br />
**[[5twv]] - rIRK 11 + sulfonylurea receptor + ATP + glibenclamide – Cryo EM<br />
**[[6pz9]], [[6pza]], [[5twv]] - rIRK 11 + SUR1 + ATP + diabetes drug – Cryo EM<br />
**[[1u4f]],[[3agw]] - mIRK 2 cytoplasmic domain<br />
**[[1u4f]],[[3agw]] - mIRK 2 cytoplasmic domain<br />
**[[2xky]] - mIRK 2 cytoplasmic domain - EM<br />
**[[2xky]] - mIRK 2 cytoplasmic domain - EM<br />
Line 135: Line 140:
**[[1n9p]], [[1u4e]] - mIRK 1 cytoplasmic domain<br />
**[[1n9p]], [[1u4e]] - mIRK 1 cytoplasmic domain<br />
**[[3k6n]] - mIRK 1 cytoplasmic domain (mutant)<br />
**[[3k6n]] - mIRK 1 cytoplasmic domain (mutant)<br />
**[[5um4]] - mIRK 3.1 (mutant)<br />
**[[3at8]], [[3at9]], [[3ata]], [[3atb]], [[3atd]], [[3ate]], [[3atf]], [[3auw]], [[3syo]] - mIRK 3.2<br />
**[[3at8]], [[3at9]], [[3ata]], [[3atb]], [[3atd]], [[3ate]], [[3atf]], [[3auw]], [[3syo]] - mIRK 3.2<br />
**[[3syc]], [[3syp]] - mIRK 3.2 (mutant) <br />
**[[3syc]], [[3syp]] - mIRK 3.2 (mutant) <br />
Line 140: Line 146:
**[[3syq]] - mIRK 3.2 (mutant) + PIP2<br />
**[[3syq]] - mIRK 3.2 (mutant) + PIP2<br />
**[[4kfm]] - mIRK 3.2 + guanine nucleotide-biding protein<br />
**[[4kfm]] - mIRK 3.2 + guanine nucleotide-biding protein<br />
**[[5wua]], [[5twv]] - mIRK 11 + sulfonylurea receptor - Cryo EM<br />
**[[5wua]], [[5twv]] - mIRK 11 + SUR1 - Cryo EM<br />
**[[5ywc]], [[5ywb]] - mIRK 11 + sulfonylurea receptor + ADP – Cryo EM<br />
**[[5ywc]], [[5ywb]] - mIRK 11 + SUR1 + ADP – Cryo EM<br />
**[[5ywa]], [[5yw9]], [[5yw8]] - mIRK 11 + sulfonylurea receptor + ATP – Cryo EM<br />
**[[5ywa]], [[5yw9]], [[5yw8]] - mIRK 11 + SUR1 + ATP – Cryo EM<br />
**[[5ykg]], [[5ykf]], [[5yke]] - mIRK 11 + sulfonylurea receptor + ATP + glibenclamide – Cryo EM<br />
**[[5ykg]], [[5ykf]], [[5yke]], [[6jb1]] - mIRK 11 + SUR1 + ATP + diabetes drug – Cryo EM<br />
**[[6m85]] – cIRK 2.2<br />
**[[3spj]], [[6m86]] – cIRK 2.2 (mutant)<br />
**[[3spc]] – cIRK 2.2 + DGPP <br />
**[[3spc]] – cIRK 2.2 + DGPP <br />
**[[3spg]], [[3sph]], [[5kum]], [[5kuk]]  – cIRK 2.2 (mutant) + PIP2<br />
**[[3spg]], [[3sph]], [[5kum]], [[5kuk]], [[6m84]]  – cIRK 2.2 (mutant) + PIP2<br />
**[[3spi]] – cIRK 2.2 + PIP2<br />
**[[3spi]] – cIRK 2.2 + PIP2<br />
**[[3spj]] – cIRK 2.2 (mutant)<br />
**[[1xl4]], [[1xl6]], [[2wlk]], [[2x6a]], [[2x6b]], [[2x6c]] - MmIRK KIRBAC3.1<br />
**[[1xl4]], [[1xl6]], [[2wlk]], [[2x6a]], [[2x6b]], [[2x6c]] - MmIRK KIRBAC3.1<br />
**[[4lp8]] - MmIRK KIRBAC3.1 (mutant) <br />
**[[4lp8]] - MmIRK KIRBAC3.1 (mutant) <br />
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