Neurotransmitters: Difference between revisions
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<scene name='82/829381/Cv/5'>Histamine</scene>. | <scene name='82/829381/Cv/5'>Histamine</scene>. | ||
==Histamine receptors== | ==Histamine receptors== | ||
Allergy symptoms are mostly caused by the release of histamine in response to allergens. The binding of histamine to the extracellular portion of the H1 receptor triggers a structural change of the transmembrane portion, leading to a change in the C terminal area. This c terminal region interacts with G proteins, leading to the activation of the Gq signalling pathway, which triggers allergy symptoms like itchy eyes and runny noses. Many allergy drugs are anti-histamines, in that they bind to the histamine receptor but do not cause the conformational change that leads to a response. | |||
[[Histamine H1 receptor]] | [[Histamine H1 receptor]] | ||
