6uqf: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6uqf is ~~ON HOLD~~

==Human HCN1 channel in a hyperpolarized conformation==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6uqf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UQF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UQF FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uqf OCA], [http://pdbe.org/6uqf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uqf RCSB], [http://www.ebi.ac.uk/pdbsum/6uqf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uqf ProSAT]</span></td></tr>

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/HCN1_HUMAN HCN1_HUMAN]] Early infantile epileptic encephalopathy. The disease is caused by mutations affecting the gene represented in this entry.

== Function ==

[[http://www.uniprot.org/uniprot/HCN1_HUMAN HCN1_HUMAN]] Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). May mediate responses to sour stimuli.<ref>PMID:15351778</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Lee, C H]]

[[Category: MacKinnon, R]]

[[Category: Ion channel]]

[[Category: Membrane protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6uqf is ON HOLD
+==Human HCN1 channel in a hyperpolarized conformation==
+<StructureSection load='6uqf' size='340' side='right'caption='[[6uqf]], [[Resolution|resolution]] 3.04&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6uqf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UQF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UQF FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uqf OCA], [http://pdbe.org/6uqf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uqf RCSB], [http://www.ebi.ac.uk/pdbsum/6uqf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uqf ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/HCN1_HUMAN HCN1_HUMAN]] Early infantile epileptic encephalopathy. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[[http://www.uniprot.org/uniprot/HCN1_HUMAN HCN1_HUMAN]] Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). May mediate responses to sour stimuli.<ref>PMID:15351778</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Lee, C H]]
+[[Category: MacKinnon, R]]
+[[Category: Ion channel]]
+[[Category: Membrane protein]]