5c25: Difference between revisions
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==Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 6-((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-5,7-dimethyl-2-naphthonitrile (JLJ639), a Non-nucleoside Inhibitor== | ==Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 6-((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-5,7-dimethyl-2-naphthonitrile (JLJ639), a Non-nucleoside Inhibitor== | ||
<StructureSection load='5c25' size='340' side='right' caption='[[5c25]], [[Resolution|resolution]] 2.84Å' scene=''> | <StructureSection load='5c25' size='340' side='right'caption='[[5c25]], [[Resolution|resolution]] 2.84Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5c25]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C25 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C25 FirstGlance]. <br> | <table><tr><td colspan='2'>[[5c25]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C25 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C25 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=639:6-({4-[(4-CYANOPHENYL)AMINO]-1,3,5-TRIAZIN-2-YL}AMINO)-5,7-+DIMETHYL-2-NAPHTHONITRILE'>639</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=639:6-({4-[(4-CYANOPHENYL)AMINO]-1,3,5-TRIAZIN-2-YL}AMINO)-5,7-+DIMETHYL-2-NAPHTHONITRILE'>639</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5c24|5c24]], [[4mfb|4mfb]], [[4o4g|4o4g]], [[4o44|4o44]], [[4kko|4kko]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5c24|5c24]], [[4mfb|4mfb]], [[4o4g|4o4g]], [[4o44|4o44]], [[4kko|4kko]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11678 HIV-1])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c25 OCA], [http://pdbe.org/5c25 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c25 RCSB], [http://www.ebi.ac.uk/pdbsum/5c25 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c25 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c25 OCA], [http://pdbe.org/5c25 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c25 RCSB], [http://www.ebi.ac.uk/pdbsum/5c25 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c25 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Hiv-1]] | |||
[[Category: Large Structures]] | |||
[[Category: Anderson, K S]] | [[Category: Anderson, K S]] | ||
[[Category: Chan, A H]] | [[Category: Chan, A H]] | ||
