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==Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 11c and CoA==
==Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 11c and CoA==
<StructureSection load='5ebv' size='340' side='right' caption='[[5ebv]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='5ebv' size='340' side='right'caption='[[5ebv]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ebv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EBV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EBV FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ebv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EBV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EBV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5LR:5-(4-CHLOROPHENYL)-~{N}-[3-(3,4-DIHYDRO-1~{H}-ISOQUINOLIN-2-YL)PROPYL]-4-METHYL-1,1-BIS(OXIDANYLIDENE)-1,2-THIAZOL-3-AMINE'>5LR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5LR:5-(4-CHLOROPHENYL)-~{N}-[3-(3,4-DIHYDRO-1~{H}-ISOQUINOLIN-2-YL)PROPYL]-4-METHYL-1,1-BIS(OXIDANYLIDENE)-1,2-THIAZOL-3-AMINE'>5LR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ec4|5ec4]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ec4|5ec4]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">eis, Rv2416c, MTCY253.04 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ebv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ebv OCA], [http://pdbe.org/5ebv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ebv RCSB], [http://www.ebi.ac.uk/pdbsum/5ebv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ebv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ebv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ebv OCA], [http://pdbe.org/5ebv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ebv RCSB], [http://www.ebi.ac.uk/pdbsum/5ebv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ebv ProSAT]</span></td></tr>
</table>
</table>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Myctu]]
[[Category: Gajadeera, C S]]
[[Category: Gajadeera, C S]]
[[Category: Garneau-Tsodikova, S]]
[[Category: Garneau-Tsodikova, S]]

Revision as of 16:06, 11 December 2019

Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 11c and CoA

5ebv, resolution 2.20Å

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