5j2m: Difference between revisions
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==HIV-1 reverse transcriptase in complex with DNA and EFdA-triphosphate, a translocation-defective RT inhibitor== | ==HIV-1 reverse transcriptase in complex with DNA and EFdA-triphosphate, a translocation-defective RT inhibitor== | ||
<StructureSection load='5j2m' size='340' side='right' caption='[[5j2m]], [[Resolution|resolution]] 2.43Å' scene=''> | <StructureSection load='5j2m' size='340' side='right'caption='[[5j2m]], [[Resolution|resolution]] 2.43Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5j2m]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J2M FirstGlance]. <br> | <table><tr><td colspan='2'>[[5j2m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J2M FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6FN:2-DEOXY-4-ETHYNYL-2-FLUOROADENOSINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)'>6FN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6FN:2-DEOXY-4-ETHYNYL-2-FLUOROADENOSINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)'>6FN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MRG:N2-(3-MERCAPTOPROPYL)-2-DEOXYGUANOSINE-5-MONOPHOSPHATE'>MRG</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MRG:N2-(3-MERCAPTOPROPYL)-2-DEOXYGUANOSINE-5-MONOPHOSPHATE'>MRG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5j2q|5j2q]], [[5j2p|5j2p]], [[5j2n|5j2n]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5j2q|5j2q]], [[5j2p|5j2p]], [[5j2n|5j2n]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11706 HIV-1])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j2m OCA], [http://pdbe.org/5j2m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j2m RCSB], [http://www.ebi.ac.uk/pdbsum/5j2m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j2m ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j2m OCA], [http://pdbe.org/5j2m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j2m RCSB], [http://www.ebi.ac.uk/pdbsum/5j2m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j2m ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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</div> | </div> | ||
<div class="pdbe-citations 5j2m" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5j2m" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Reverse transcriptase|Reverse transcriptase]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Hiv-1]] | |||
[[Category: Large Structures]] | |||
[[Category: Kirby, K A]] | [[Category: Kirby, K A]] | ||
[[Category: Salie, Z L]] | [[Category: Salie, Z L]] | ||
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[[Category: Efda-tp]] | [[Category: Efda-tp]] | ||
[[Category: Efda-triphosphate]] | [[Category: Efda-triphosphate]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Nrti]] | [[Category: Nrti]] | ||
