Tutorial:The opioid receptor, a molecular switch: Difference between revisions
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Once an individual takes an opioid medication, the aforementioned process transpires. When the arrestin begins to alter the cell's environment, it has with it a secondary effect. The process arrestin causes also develops drug tolerance[https://en.wikipedia.org/wiki/Drug_tolerance], which makes the body more resistant to the pain-numbing and dopamine-releasing effects brought about by the presence of opioids in the body. Furthermore, the psychological impact of low pain and high dopamine result in the body desiring this effect from said opioids. Altogether, this sets the body up to take more and more opioids to get this feeling, and, in turn, building more and more tolerance. Attempting to go off of the drugs by this point results in withdrawal[https://en.wikipedia.org/wiki/Drug_withdrawal], which throws off the body's systems and the chemicals in the brain, altering personality and inflicting crippling side-effects. | Once an individual takes an opioid medication, the aforementioned process transpires. When the arrestin begins to alter the cell's environment, it has with it a secondary effect. The process arrestin causes also develops drug tolerance[https://en.wikipedia.org/wiki/Drug_tolerance], which makes the body more resistant to the pain-numbing and dopamine-releasing effects brought about by the presence of opioids in the body. Furthermore, the psychological impact of low pain and high dopamine result in the body desiring this effect from said opioids. Altogether, this sets the body up to take more and more opioids to get this feeling, and, in turn, building more and more tolerance. Attempting to go off of the drugs by this point results in withdrawal[https://en.wikipedia.org/wiki/Drug_withdrawal], which throws off the body's systems and the chemicals in the brain, altering personality and inflicting crippling side-effects. | ||
When untreated, opioid overdose kills people because they stop breathing. The drug naloxone can prevent overdose deaths when administered in time. [https://youtu.be/_LFWsDXLnkI <span class="fas fa-video" style="color:#338fff"></span>] | When untreated, opioid overdose kills people because they stop breathing. The drug naloxone[https://en.wikipedia.org/wiki/Naloxone] can prevent overdose deaths when administered in time. [https://youtu.be/_LFWsDXLnkI <span class="fas fa-video" style="color:#338fff"></span>] | ||
The continual presence of opioids in the body can have with it other effects. Within pregnant mothers, it may result in what is known as Neonatal Abstinence Syndrome (NAS) [https://www.youtube.com/watch?v=gxQcXtS6lG4 <span class="fas fa-video" style="color:#338fff"></span>], in which the fetus develops withdrawal symptoms after birth. This is due to the drugs passing through the placenta into the newborn's body prior to birth. Essentially, the infant becomes addicted before even being born, which, in turn, inflicts a myriad of health complications, some of which possibly fatal. | The continual presence of opioids in the body can have with it other effects. Within pregnant mothers, it may result in what is known as Neonatal Abstinence Syndrome (NAS) [https://www.youtube.com/watch?v=gxQcXtS6lG4 <span class="fas fa-video" style="color:#338fff"></span>], in which the fetus develops withdrawal symptoms after birth. This is due to the drugs passing through the placenta into the newborn's body prior to birth. Essentially, the infant becomes addicted before even being born, which, in turn, inflicts a myriad of health complications, some of which possibly fatal. | ||
