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| </StructureSection> | | </StructureSection> |
| == 3D Structures of Reverse transcriptase ==
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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| {{#tree:id=OrganizedByTopic|openlevels=0|
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| * HIV-1 reverse transcriptase P66/P51
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| **[[3dlk]], [[1hmv]] - P66/P51<br />
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| **[[1mu2]], [[1jle]], [[1hpz]], [[1hqu]], [[1qe1]], [[1dlo]], [[2wom]], [[2won]], [[3tam]], [[4dg1]], [[4zhr]], [[4ifv]] - P66/P51 (mutant)<br />
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| **[[3qip]] - P66/P51 + NNRTI + RNase H inhibitor<br />
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| **[[3irx]], [[3is9]], [[3lak]], [[3lal]], [[3lam]], [[3lan]], [[3ffi]], [[3di6]], [[3dle]], [[3dlg]], [[2rki]], [[3c6t]], [[3c6u]], [[2rf2]], [[2vg5]], [[2vg6]], [[2vg7]], [[2opp]], [[1jlq]], [[1ep4]], [[1c0t]], [[1c0u]], [[1dtt]], [[1dtq]], [[1bqm]], [[1rt1]], [[1rt2]], [[1rev]], [[1rtj]], [[1vru]], [[1hnv]], [[1hni]], [[3t19]], [[5ki4]], [[5fdl]], [[5c24]], [[5c25]], [[4rw7]], [[5ter]], [[5k14]], [[2ynh]], [[2yni]], [[4ncg]], [[1c1b]], [[3lp0]], [[3lp1]], [[3lp2]], [[1vrt]], [[3hvt]], [[4i7f]], [[3m8p]], [[3mec]], [[3mee]], [[2zd1]], [[3qlh]], [[1ikw]], [[1fk9]], [[3dya]], [[3e01]], [[3drp]] - P66/P51+NNRTI<br />
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| **[[1s1t]], [[1s1v]], [[1s1w]], [[1s6p]], [[1s6q]], [[1s9e]], [[1s9g]], [[1suq]], [[1sv5]], [[3dm2]], [[3dmj]], [[3dok]], [[3dol]], [[2opq]], [[2opr]], [[2ops]], [[2ic3]], [[2hnz]], [[1jlg]], [[1bqn]], [[1uwb]], [[1tvr]], [[3qo9]], [[3t1a]], [[5c42]], [[5tw3]], [[4rw4]], [[4rw6]], [[4rw8]], [[2ynf]], [[2yng]], [[2ynf]], [[2yng]], [[4kko]], [[4lsl]], [[4lsn]], [[4mfb]], [[4o44]], [[4o4g]], [[1lw2]], [[1rt3]], [[6duh]], [[6dug]], [[6duf]], [[6cgf]], [[6c0r]], [[1jla]], [[6c0p]], [[6c0o]], [[6c0n]], [[6c0l]], [[6c0k]], [[6c0j]], [[5vqz]], [[5vqy]], [[5vqx]], [[5vqw]], [[5vqv]], [[5vqu]], [[5vqt]], [[5vqs]], [[5vqr]], [[5vqq]], [[5tep]], [[2ykm]], [[2ykn]], [[4h4m]], [[4h4o]], [[4rw4]], [[4rw6]], [[4rw7]], [[4rw8]], [[4rw9]], [[2iaj]], [[2hnd]], [[2hny]], [[1s1u]], [[1s1x]], [[1lw0]], [[1lwc]], [[1lwe]], [[1lwf]], [[1jlb]], [[1jlf]], [[1fkp]], [[3med]], [[3meg]], [[2ze2]], [[4g1q]], [[4icl]], [[4id5]], [[4idk]], [[4ify]], [[4ig0]], [[4ig3]], [[4kfb]], [[1jkh]], [[1ikv]], [[1fko]], [[3drr]], [[3drs]], [[6dtw]], [[6dtx]] - P66/P51 (mutant)+NNRTI<br />
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| **[[4qag]] – Hiv1P66 + coumarin derivative <br />
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| **[[1rti]] - P66/P51+ inhibitor<br />
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| **[[3ig1]] - P66/P51 + inhibitor beta-thujaplicinol<br />
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| **[[3i0r]], [[3i0s]], [[3m8q]], [[3isn]], [[3ith]], [[1c1c]], [[3nbp]], [[5vz6]] - P66/P51+ pyrimidine derivative<br />
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| **[[1ikx]], [[4ko0]], [[4we1]], [[6aoc]], [[5tuq]], [[6oe3]] - P66/P51 (mutant)+ pyrimidine derivative<br />
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| **[[1tv6]] - P66/P51+ pyridine derivative<br />
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| **[[6eli]] - P66/P51+ pyridine derivative + rilpivirine + gag-pol polyprotein<br />
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| **[[1jlc]], [[1iky]], [[1eet]] - P66/P51 (mutant) + pyridine derivative<br />
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| **[[5cym]], [[5cyq]] - P66/P51 (mutant) + pyrazole derivative<br />
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| **[[2b5j]], [[2ban]], [[2be2]], [[1rth]], [[4kv8]] - P66/P51+ pyridone derivative<br />
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| **[[5j1e]], [[5hbm]] - P66/P51 (mutant) + pyridone derivative<br />
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| **[[6ecl]] - P66/P51 (mutant) + triazole derivative<br />
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| **[[6o9e]] - P66/P51 (mutant) + pyridone derivative + CMP<br />
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| **[[1tkt]], [[1tkx]], [[1tkz]], [[1tl1]], [[1tl3]] - P66/P51+ quinoline derivative<br />
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| **[[5uv5]] - P66/P51 (mutant) + quinoline derivative <br />
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| **[[2b6a]] - P66/P51+ THR-50<br />
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| **[[2i5j]] - P66/P51 (mutant)+hydrazone derivative<br />
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| **[[1rt4]], [[1rt5]], [[1rt6]], [[1rt7]] - P66/P51+ carboxanilide derivative<br />
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| **[[1klm]] - P66/P51+piperazine derivative<br />
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| * HIV-1 reverse transcriptase complex with DNA/RNA
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| **[[3kjv]], [[3kk3]], [[1r0a]], [[1n5y]], [[1n6q]], [[1hys]], [[5d3g]], [[5i3u]] - P66/P51+DNA<br />
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| **[[1j5o]], [[1rtd]], [[3klf]], [[3v4i]], [[3v6d]], [[6avt]], [[6avm]], [[6asw]], [[5j2q]], [[5j2p]], [[5j2m]], [[6or7]], [[6otz]], [[6oun]], [[6bhj]] - P66/P51 (mutant)+DNA<br />
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| **[[4r5p]], [[5j2n]], [[5txo]], [[5txp]] - P66/P51 (mutant) + nucleotide + DNA<br />
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| **[[3v81]] - P66/P51 (mutant) + DNA + NNRTI<br />
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| **[[1hvu]] - P66/P51+RNA<br />
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| **[[4b3o]], [[4b3p]], [[4b3q]], [[6bsj]], [[6bsi]], [[6bsh]], [[6bsg]] - P66/P51 + RNA + DNA<br />
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| **[[4pqu]] - P66/P51 (mutant) + dATP + RNA + DNA<br />
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| **[[5i42]] - P66/P51 + dTTP + DNA<br />
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| **[[6anq]], [[6an8]], [[6an2]], [[6amo]] - P66/P51 (mutant) + dTTP + DNA<br />
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| **[[6p1i]], [[6p1x]], [[6p2g]] - P66/P51 (mutant) + dCTP + DNA<br />
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| **[[6ik9]] - P66/P51 (mutant) + dCMP + GTP + DNA<br />
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| **[[5txn]], [[5txm]], [[5txl]] - P66/P51 (mutant) + dATP + DNA<br />
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| **[[6b19]] - P66/P51 (mutant) + tRNA + RNA<br />
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| **[[4puo]], [[4pwd]], [[4q0b]] - P66/P51 (mutant) + NNRTI + RNA + DNA<br />
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| **[[1t03]], [[1t05]] - P66/P51+DNA+Fab+NNRTI<br />
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| **[[3jsm]] - P66/P51 (mutant)+DNA+NNRTI<br />
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| **[[2hmi]] - P66/P51 (mutant)+DNA+Fab<br />
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| **[[3kk1]] - P66/P51 (mutant)+DNA + inhibitor<br />
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| **[[3kk2]] - P66/P51+DNA+NNRTI<br />
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| **[[3jyt]] - P66/P51 (mutant)+DNA+NNRTI<br />
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| **[[4r5p]], [[5hlf]], [[5hp1]], [[5hro]] - P66/P51 + DNA + phosphonate inhibitor<br />
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| *HIV-1 AZT-resistant reverse transcriptase P66/P51
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| **[[3kli]] - P66/P51 (mutant)<br />
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| **[[3kle]], [[3klg]], [[3klh]] – P66/P51 (mutant) + DNA
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| *HIV-1 reverse transcriptase P66
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| **[[2jle]] – P66+NNRTI<br />
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| **[[1har]] - P66 N-terminal<br />
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| **[[5t82]] - P66 thumb domain - NMR<br />
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| *Hiv-1 P15
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| **[[1rdh]], [[1hrh]], [[5dzm]] – P15<br />
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| **[[3lp3]] – P15+inhibitor MK3<br />
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| **[[3k2p]] – P15+inhibitor beta-thujaplicinol<br />
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| **[[3hyf]] – P15+pyrimidine derivative<br />
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| **[[1o1w]] – P15+Mg - NMR<br />
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| *HIV-2 reverse transcriptase
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| **[[1mu2]] - RT (mutant)
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| * Moloney murine leukemia virus reverse transcriptase
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| **[[1mml]] - MmlvRT residues 130-394<br />
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| **[[1nnd]] - MmlvRT catalytic fragment residues 144-398 (mutant)<br />
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| **[[2r2r]], [[2r2t]], [[2fjv]], [[2fjw]], [[2fjx]], [[1ztw]], [[2fvs]], [[2fvr]], [[2fvq]], [[2fvp]], [[1n4l]] - MmlvRT catalytic fragment residues 144-398 +DNA<br />
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| **[[2r2s]], [[2r2u]] – MmlvRT catalytic fragment residues 144-398 +DNA+Co Bleomycin<br />
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| **[[1ztt]] – MmlvRT catalytic fragment residues 144-398 +DNA+netropsin<br />
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| **[[3fsi]] – MmlvRT catalytic fragment residues 144-398 +DNA+trypanocidal<br />
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| **[[2hb5]] – MmlvRT RNAse domain residues 618-791<br />
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| **[[4xo0]], [[4xpc]], [[4xpe]], [[5vbs]], [[4m94]], [[4m95]], [[6b1q]], [[6b1r]], [[6b1s]] – MmlvRT catalytic fragment residues 683-937 +DNA<br />
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| **[[4mh8]] – MmlvRT P80 residues 683-1330 (mutant)<br />
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| **[[1i6j]], [[1d0e]], [[1d1u]], [[1qaj]], [[1qai]], [[6mih]], [[6mik]] – MmlvRT N-terminal+DNA<br />
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| *Xenotropic mulv-related virus reverse transcriptase
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| **[[3v1o]], [[3v1q]] – RNAse H domain<br />
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| **[[3v1r]] – RNAse H domain + inhibitor<br />
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| **[[4hkq]] – RT residues 658-1328 (mutant) + DNA + RNA<br />
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| *Telomerase reverse transcriptase see [[Telomerase]]
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| *other RT
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| **[[2lsn]] – RT – Simian foamy virus – NMR<br />
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| **[[4ol8]] - P55 (mutant) + RNA + DNA - yeast<br />
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| }}
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| ==See Also== | | ==See Also== |
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