6mha: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6mha is ~~ON HOLD until Paper Publication~~

==dHP1 Chromodomain Y24W variant bound to histone H3 peptide containing trimethyllysine==

~~Authors~~: ~~Brustad~~, E.M., ~~Krone, M~~.W., ~~Albanese~~, K.I., ~~Waters~~, M.L.

== Structural highlights ==

<table><tr><td colspan='2'>[[6mha]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MHA OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MHA FirstGlance].

~~Description~~: ~~dHP1 Chromodomain Y24W variant bound to~~ histone H3 ~~peptide containing trimethyllysine~~

</td></tr><tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[1kne|1kne]]</td></tr>

[[Category: ~~Krone~~, ~~M.W~~]]

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">Su(var)205, HP1, CG8409 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>

[[Category: Brustad, E.M]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mha OCA], [http://pdbe.org/6mha PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mha RCSB], [http://www.ebi.ac.uk/pdbsum/6mha PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mha ProSAT]</td></tr>

[[Category: ~~Albanese~~, ~~K.I~~]]

</table>

[[Category: Waters, M.L]]

== Function ==

[[http://www.uniprot.org/uniprot/HP1_DROME HP1_DROME]] Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression.

__TOC__

</StructureSection>

[[Category: Drome]]

[[Category: Large Structures]]

[[Category: Albanese, K I]]

[[Category: Brustad, E M]]

[[Category: Krone, M W]]

[[Category: Waters, M L]]

[[Category: Cation-pi epigenetics trimethyllysine chromodomain]]

[[Category: Protein binding]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6mha is ON HOLD  until Paper Publication
+==dHP1 Chromodomain Y24W variant bound to histone H3 peptide containing trimethyllysine==
+<StructureSection load='6mha' size='340' side='right'caption='[[6mha]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-Authors: Brustad, E.M., Krone, M.W., Albanese, K.I., Waters, M.L.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6mha]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MHA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MHA FirstGlance]. <br>
-Description: dHP1 Chromodomain Y24W variant bound to histone H3 peptide containing trimethyllysine
+</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kne|1kne]]</td></tr>
-[[Category: Krone, M.W]]
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Su(var)205, HP1, CG8409 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
-[[Category: Brustad, E.M]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mha OCA], [http://pdbe.org/6mha PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mha RCSB], [http://www.ebi.ac.uk/pdbsum/6mha PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mha ProSAT]</span></td></tr>
-[[Category: Albanese, K.I]]
+</table>
-[[Category: Waters, M.L]]
+== Function ==
+[[http://www.uniprot.org/uniprot/HP1_DROME HP1_DROME]] Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression.
+__TOC__
+</StructureSection>
+[[Category: Drome]]
+[[Category: Large Structures]]
+[[Category: Albanese, K I]]
+[[Category: Brustad, E M]]
+[[Category: Krone, M W]]
+[[Category: Waters, M L]]
+[[Category: Cation-pi epigenetics trimethyllysine chromodomain]]
+[[Category: Protein binding]]