6ndn: Difference between revisions
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==Crystal Structure of Selenocysteine Lyase from Escherichia coli== | |||
<StructureSection load='6ndn' size='340' side='right'caption='[[6ndn]], [[Resolution|resolution]] 1.77Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ndn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NDN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NDN FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ndn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ndn OCA], [http://pdbe.org/6ndn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ndn RCSB], [http://www.ebi.ac.uk/pdbsum/6ndn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ndn ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/T9SRD8_ECOLX T9SRD8_ECOLX]] Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo.[HAMAP-Rule:MF_01831][RuleBase:RU004506] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Brandao-Neto, J]] | [[Category: Brandao-Neto, J]] | ||
[[Category: Pereira, H | [[Category: Pereira, H M]] | ||
[[Category: Scortecci, J | [[Category: Scortecci, J F]] | ||
[[Category: Thiemann, O | [[Category: Thiemann, O H]] | ||
[[Category: Enzyme]] | |||
[[Category: Lyase]] | |||
[[Category: Selenocysteine lyase]] | |||
Revision as of 09:07, 25 December 2019
Crystal Structure of Selenocysteine Lyase from Escherichia coli
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