6tyd: Difference between revisions
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==Structure of human LDB1 in complex with SSBP2== | |||
<StructureSection load='6tyd' size='340' side='right'caption='[[6tyd]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6tyd]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TYD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TYD FirstGlance]. <br> | |||
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tyd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tyd OCA], [http://pdbe.org/6tyd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tyd RCSB], [http://www.ebi.ac.uk/pdbsum/6tyd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tyd ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/LDB1_HUMAN LDB1_HUMAN]] Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Play a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Wang, H]] | |||
[[Category: Wang, Z]] | |||
[[Category: Xu, W]] | |||
[[Category: Chil]] | |||
[[Category: Ldb1]] | |||
[[Category: Ssbp2]] | |||
[[Category: Transcription]] | |||
Revision as of 08:28, 1 January 2020
Structure of human LDB1 in complex with SSBP2
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