5wkm: Difference between revisions
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==2.25 A resolution structure of MERS 3CL protease in complex with piperidine-based peptidomimetic inhibitor 21== | ==2.25 A resolution structure of MERS 3CL protease in complex with piperidine-based peptidomimetic inhibitor 21== | ||
<StructureSection load='5wkm' size='340' side='right' caption='[[5wkm]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='5wkm' size='340' side='right'caption='[[5wkm]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5wkm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WKM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WKM FirstGlance]. <br> | <table><tr><td colspan='2'>[[5wkm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mers Mers]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WKM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WKM FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B6Y:(1R,2S)-2-{[N-({[1-(tert-butoxycarbonyl)-4-ethylpiperidin-4-yl]oxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic+acid'>B6Y</scene>, <scene name='pdbligand=N02:(1S,2S)-2-{[N-({[1-(tert-butoxycarbonyl)-4-ethylpiperidin-4-yl]oxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic+acid'>N02</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B6Y:(1R,2S)-2-{[N-({[1-(tert-butoxycarbonyl)-4-ethylpiperidin-4-yl]oxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic+acid'>B6Y</scene>, <scene name='pdbligand=N02:(1S,2S)-2-{[N-({[1-(tert-butoxycarbonyl)-4-ethylpiperidin-4-yl]oxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic+acid'>N02</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">orf1a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1335626 MERS])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wkm OCA], [http://pdbe.org/5wkm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wkm RCSB], [http://www.ebi.ac.uk/pdbsum/5wkm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wkm ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wkm OCA], [http://pdbe.org/5wkm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wkm RCSB], [http://www.ebi.ac.uk/pdbsum/5wkm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wkm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Mers]] | |||
[[Category: Battaile, K P]] | [[Category: Battaile, K P]] | ||
[[Category: Chang, K O]] | [[Category: Chang, K O]] | ||
Revision as of 09:55, 1 January 2020
2.25 A resolution structure of MERS 3CL protease in complex with piperidine-based peptidomimetic inhibitor 21
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