Sandbox Reserved 1099: Difference between revisions
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The gene DCD is located on the chromosome 12 and has no homology with other known antimicrobial peptides. Indeed, there are already two classes of mammalian antimicrobial peptides known : | The gene DCD is located on the chromosome 12 and has no homology with other known antimicrobial peptides. Indeed, there are already two classes of mammalian antimicrobial peptides known : | ||
*[https://en.wikipedia.org/wiki/Cathelicidin_ Cathelicidins] | *[https://en.wikipedia.org/wiki/Cathelicidin_ Cathelicidins] | ||
*[https://fr.wikipedia.org/wiki/Défensine_ Defensins] (α-defensins and β-defensins) | *[https://fr.wikipedia.org/wiki/Défensine_ Defensins] which are cationic peptides (α-defensins and β-defensins) | ||
Dermcidin gene is expressed as precursor only in eccrine sweat glands within the dermis of the skin and the derived-peptide is secreted by granules. | |||
== Structural highlights == | == Structural highlights == | ||
size, proteolytically processed | |||
== Antimicrobial activity == | == Antimicrobial activity == | ||
