6czb: Difference between revisions

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'''Unreleased structure'''


The entry 6czb is ON HOLD  until Paper Publication
==Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with uridine triphosphate (UTP) - promiscuous binding mode with disordered nucleoside==
 
<StructureSection load='6czb' size='340' side='right'caption='[[6czb]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
Authors: Thompson, A.P., Wegener, K.L., Bruning, J.B., Polyak, S.W.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6czb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CZB FirstGlance]. <br>
Description: Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with uridine triphosphate (UTP) -promiscuous binding mode with disordered nucleoside
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wop|4wop]], [[3fgn|3fgn]], [[3fmf|3fmf]], [[6cve|6cve]], [[6cvu|6cvu]], [[6cvv|6cvv]], [[6cvf|6cvf]], [[3fpa|3fpa]], [[3fmi|3fmi]], [[6czc|6czc]], [[6czd|6czd]], [[6cze|6cze]]</td></tr>
[[Category: Polyak, S.W]]
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bioD, Rv1570, MTCY336.33c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
[[Category: Bruning, J.B]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dethiobiotin_synthase Dethiobiotin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.3.3 6.3.3.3] </span></td></tr>
[[Category: Thompson, A.P]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6czb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6czb OCA], [http://pdbe.org/6czb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6czb RCSB], [http://www.ebi.ac.uk/pdbsum/6czb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6czb ProSAT]</span></td></tr>
[[Category: Wegener, K.L]]
</table>
== Function ==
[[http://www.uniprot.org/uniprot/BIOD_MYCTU BIOD_MYCTU]] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.<ref>PMID:20565114</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Dethiobiotin synthase]]
[[Category: Large Structures]]
[[Category: Myctu]]
[[Category: Bruning, J B]]
[[Category: Polyak, S W]]
[[Category: Thompson, A P]]
[[Category: Wegener, K L]]
[[Category: Enzyme]]
[[Category: Nucleotide triphosphate binding]]
[[Category: Synthetase]]
[[Category: Transferase]]
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