Sandbox Reserved 1095: Difference between revisions
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Lys199 : an important role for AngII binding | Lys199 : an important role for AngII binding | ||
=== Interaction with other GPCRs=== | ==== Interaction with other GPCRs==== | ||
It has been showed that AT1Rs were also able to bind with other GPCRs to form homo- or heterodimers. Those interactions can modify the sensitivity of the receptor, which leads to different physiological and pathological conditions than the GPCR monomer <ref> http://www.jbc.org/content/290/49/29127 </ref> <ref>https://doi.org/10.1016/j.phrs.2017.06.013 </ref>. | It has been showed that AT1Rs were also able to bind with other GPCRs to form homo- or heterodimers. Those interactions can modify the sensitivity of the receptor, which leads to different physiological and pathological conditions than the GPCR monomer <ref> http://www.jbc.org/content/290/49/29127 </ref> <ref>https://doi.org/10.1016/j.phrs.2017.06.013 </ref>. | ||
